Clinically reviewed guidance on menopause hormone therapy, estradiol, progesterone, testosterone replacement therapy, thyroid treatment, monitoring labs, contraindications, and safety.
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2026-05-27latest review
What is hormone replacement therapy?
Hormone replacement therapy replaces hormones that decline with age or are low due to a medical condition. In women it most often means estrogen, usually with progesterone, for menopause. In men it means testosterone replacement, often called TRT.
How does HRT work?
HRT supplies the hormone the body is missing, through patches, gels, injections, pills, or vaginal preparations. Restoring more typical hormone levels can relieve symptoms and, in some cases, support bone and metabolic health.
Who is HRT for, and what does it treat?
HRT is used when symptoms and lab testing point to low or declining hormones. The right approach depends on sex, age, symptoms, and medical history.
Menopause symptoms: hot flashes, night sweats, vaginal dryness, sleep and mood changes.
Low testosterone in men: low energy, reduced libido, loss of muscle, and mood changes.
Bone health support in appropriate candidates.
Thyroid hormone replacement is a separate, related area of hormone medicine.
Is HRT safe, and what are the risks?
For many people HRT is safe and effective when matched to their situation, but the risks and benefits depend on the hormone, the dose, the route, age, and timing. Women's HRT decisions weigh symptom relief and bone benefits against certain risks, and men's TRT requires monitoring of blood counts and prostate health. These are individualized decisions made with a clinician.
How do you get HRT online?
Getting HRT online starts with an evaluation and lab testing ordered by a licensed provider, who reviews your symptoms and history and, if appropriate, prescribes therapy with ongoing monitoring. Hormones are prescription only and should not be used without medical oversight.
Frequently asked questions
What is hormone replacement therapy?
HRT restores hormones that decline with age. In women it usually means estrogen and progesterone for menopause; in men it means testosterone replacement (TRT).
What is TRT?
TRT is testosterone replacement therapy, used to treat low testosterone in men, with symptoms like low energy, reduced libido, and loss of muscle.
Is HRT safe?
HRT can be safe and effective when matched to the individual, but risks and benefits depend on the hormone, dose, route, age, and timing, so it is decided with a clinician.
How do I get HRT or TRT online?
You start with an evaluation and lab testing ordered by a licensed provider, who can prescribe therapy with ongoing monitoring if appropriate.