HealthRX.com · Printable titration log
Slow weight loss on tirzepatide: dose history and weight record for the review visit
Fill this in before a review when weight is changing less than expected: dated weights with your percentage change, each dose and how long you actually took it, missed or delayed injections, side effects and other medicines. The facts box gives what SURMOUNT-1, NICE and the label say about timing and doses.
Starting point
Starting weight and date
Reason prescribedtype 2 diabetes or weight management
Goal agreed at the start
Product and deviceMounjaro or Zepbound; pen, vial or KwikPen
Dose history
| Dose (mg) | Start date | End date | Weeks actually taken | Missed or delayed injections | Why it changed |
|---|---|---|---|---|---|
Weight record
Percentage change = (starting weight minus current weight) divided by starting weight, times 100.
| Date | Weight | Change from start (%) | Appetite, meals and activity |
|---|---|---|---|
Also bring
- Glucose results or HbA1c, if you have diabetes
- Any change to insulin, a sulfonylurea, a steroid or a psychiatric medicine
- Side effects that led to missed or lowered doses
- How the pen or vial has been stored
- A few days of food and drink notes
What the sources say
- In SURMOUNT-1, 70% of people who had lost under 5% by week 12 had reached 5% by week 24, and 90% by week 72.[1]
- NICE's review point is 6 months on the highest tolerated dose; below 5% loss, the reasons are discussed and a decision is made about continuing.[2]
- NICE notes that people with type 2 diabetes may take longer to lose weight.[2]
- Zepbound's maintenance doses are 5 mg, 10 mg and 15 mg; 2.5 mg is only for starting treatment.[3]
Not a plateau: call now
- Severe stomach pain that will not go away, with or without vomiting: stop Mounjaro and call your healthcare provider right away.[4]
Questions for the review
- Have I been on my current dose long enough to judge it?
- Would a dose change, a different medicine or more nutrition support help most?
- Could one of my other medicines be working against weight loss?
- Is a thyroid test worth doing, and is any other test needed for a specific reason?
- What result by what date would make us change the plan?
Sources for the facts on this sheet
- Ard J, Lee CJ, Gudzune K, et al. Weight reduction over time in tirzepatide-treated participants by early weight loss response: Post hoc analysis in SURMOUNT-1. Diabetes Obes Metab 2025. PMID 40677091. https://pubmed.ncbi.nlm.nih.gov/40677091/
- National Institute for Health and Care Excellence (NICE). Prescribing, reviewing and stopping tirzepatide | Tools and resources | Overweight and obesity management | Guidance | NICE. Accessed 2026-10-19. https://www.nice.org.uk/guidance/ng246/resources/a-guide-for-prescribing-medicines-to-manage-overweight-and-obesity-15299628589/chapter/Prescribing-reviewing-and-stopping-tirzepatide
- Eli Lilly and Company, via DailyMed. Zepbound (tirzepatide) injection, for subcutaneous use: prescribing information and Medication Guide. Effective 2026-08-28. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=487cd7e7-434c-4925-99fa-aa80b1cc776b
- Eli Lilly and Company, via DailyMed. Mounjaro (tirzepatide) injection, for subcutaneous use: prescribing information and Medication Guide. Effective 2026-08-27. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d2d7da5d-ad07-4228-955f-cf7e355c8cc0
This sheet records information for a conversation with your prescriber or pharmacist. It does not replace their instructions or the medication's prescribing information.