Raises your own testosterone
Works upstream to stimulate your body's natural production, rather than replacing the hormone from outside.
- 60 capsulesSupply
- 3 strengthsSet by your provider
- Provider reviewedBefore anything ships
The people pictured are models, not patients.
RxHormone Therapy
Enclomiphene
Your own testosterone, prompted, not replaced.
40,000+ products sold · LegitScript certified
Enclomiphene · Provider-guided hormone support
- Raises your own T
- Oral capsule
- Fertility-preserving
- Provider-titrated
What's Included
- ✓Medication and supplies
- ✓Provider visit and unlimited follow-ups
- ✓Free expedited shipping
Pause, change, or cancel anytime from your account.
How Would You Like To Pay?
Choose Your Plan
1-Month Plan
$206- $206 Billed Today
- Then $206 Every Month
- Cancel Anytime
Or pay with
$206 billed today, then every month until canceled.
Not prescribed? Full refund.
After checkout you complete a short medical review in your member portal, and a US-licensed provider reviews it before anything ships.
Full refund if not prescribed Free, discreet shipping Cancel anytime
Order today and here is what happens next
- TodayChoose a plan, then a short online intake
- Within about 24 hoursA US-licensed provider reviews your request
- Ships in 3 to 5 daysEstimated ship date, if prescribed
- Full refund
- If a provider does not prescribe it
- Licensed clinicians
- An independent US-licensed clinician reviews every request
- US-licensed pharmacy
- Prepares and ships your prescription
- Discreet delivery
- Plain, unmarked packaging
Common questions
What is enclomiphene?
Enclomiphene is an oral medication that signals your body to make more of its own testosterone, instead of replacing it the way injections do.
Is enclomiphene FDA-approved?
No. There is no FDA-approved enclomiphene product, so this plan is compounded by a US-licensed pharmacy and prescribed off-label. FDA lists enclomiphene citrate in Category 1 of the bulk drug substances nominated for 503A compounding, which means it is under evaluation, not approved.
How much does enclomiphene cost at HealthRX.com?
The plan selector on this page shows the current price of each plan before checkout, with a lower price when you subscribe and a lower monthly rate on longer plans. Each plan includes the medication, the online provider visit with follow-up messages, and shipping. Lab tests are not listed as part of the plan, so confirm with the care team how your baseline and follow-up labs will be handled. If the provider does not prescribe, you get a full refund.
LegitScript certifiedCert. 50087439- US-licensed pharmacyPrepares every prescription
- Independent cliniciansUS-licensed, in your state
- 40,000+Products sold
- All 50 statesFree, discreet shipping
- No insurance requiredOne price, shown up front
Before work
Your own testosterone, prompted, not replaced.
- 01Raises your own T
- 02Oral capsule
- 03Fertility-preserving
- 04Provider-titrated
The people pictured are models, not patients.
Why Enclomiphene
One daily capsule
No injections, gels, or needles. A single oral capsule taken once a day.
Studied to preserve fertility
Unlike testosterone replacement, it is studied to maintain the LH, FSH, and sperm markers tied to fertility.
A provider reviews your labs
A US-licensed provider reads your bloodwork first and prescribes only if it fits. Real pricing, shown up front.
How we compare
Enclomiphene, without the waiting room.
HealthRX.comTypical in-person visit
Start online, no appointment or waiting roomBook, travel and wait
A US-licensed clinician reviews your history
Price shown before you startDepends on the visit and insurance
No insurance requiredOften billed through insurance
Delivered to your door in a plain boxPick up at the pharmacy
Full refund if you are not prescribedVisit fees usually apply either way
Understand your treatment
Stimulate production rather than supply testosterone.
Enclomiphene is a selective estrogen-receptor modulator. Its role in male hormone care is to stimulate the signaling that leads to the body producing testosterone, rather than delivering testosterone itself. This is the central distinction from testosterone cream and testosterone cypionate. Studies have examined testosterone, luteinizing hormone, follicle-stimulating hormone and sperm counts, which helps explain why the conversation extends beyond a single testosterone number.
A closer look
Stimulate production rather than supply testosterone.
Hormone feedback
LH / FSH signaling
Endogenous testosterone
Make a more informed choice
Enclomiphene vs. testosterone replacement
Enclomiphene acts on the signaling axis. Testosterone replacement supplies the hormone directly. Comparing them begins with hormone measurements and your goals, not simply choosing an oral product over a topical or injectable one.
Explore the ingredient research
- Enclomiphene compared with testosterone gel
- Phase II trial results and adverse events, enclomiphene vs topical testosterone (NCT01270841)
- Phase II trial results and adverse events, three enclomiphene doses (NCT01386606)
- Clomiphene citrate prescribing information (DailyMed)
- FDA: bulk drug substances nominated for 503A compounding (categories, May 14, 2026)
HealthRX.com verified facts
Enclomiphene online: price and access
Enclomiphene starts at $165 per month on 12-month plan; the lowest checkout charge is $206 (billed monthly). A prescription is never guaranteed. A licensed provider reviews each request before a pharmacy can dispense treatment.
Catalog verified August 26, 2026. Source: HealthRX.com checkout catalog and refund policy. Monthly equivalent divides the discounted plan charge by the number of months; checkout may collect a multi-month total.
A straightforward path to care
Select your plan
Choose your treatment options and complete secure checkout. Then complete the online health intake.
Provider review
A US-licensed provider reviews your testosterone and history, then prescribes if it is appropriate.
Ships to your door
A US-licensed pharmacy compounds your dose and ships it free in discreet packaging.
Ongoing support
Repeat bloodwork tracks your response, and your provider tunes the dose to your labs.
- Provider review
- An independent US-licensed clinician reviews every request.
- Free, discreet shipping
- Filled by a US-licensed pharmacy and shipped in discreet packaging.
- Not prescribed?
- You get a full refund for the medication.
About Enclomiphene
Enclomiphene works upstream. It signals your pituitary to release more LH and FSH, which tells your body to make more of its own testosterone, instead of replacing it the way injections do. It is a once-daily capsule, studied to preserve fertility markers. Your provider reviews your labs first, and the pharmacy compounds and ships your dose.
- Raises your own testosterone, not a replacement
- Oral capsule, no injections
- Studied to preserve fertility markers versus TRT
- Provider reviews your labs first, real pricing up front
Enclomiphene is the trans-isomer of clomiphene, a selective estrogen receptor modulator that raises LH and FSH. Compounded by a US-licensed pharmacy.
Enclomiphene
blocks the estrogen receptor at the pituitary
Pituitary gland
releases more LH and FSH
Testes
produce more of your own testosterone
In trials, testosterone rose while sperm counts stayed in the normal range.
What the research shows
Enclomiphene has been evaluated in randomized clinical trials in men with low testosterone. Here is what that research found.
Normal range
In randomized phase II and phase III trials, enclomiphene raised morning total testosterone into the normal range in men with secondary hypogonadism.
Wiehle et al., Fertil Steril 2014; Kim et al., BJU Int 2016
Sperm preserved
Enclomiphene maintained sperm concentration and raised LH and FSH, where topical testosterone lowered them in the same trials.
Kim et al., BJU Int 2016
1x / day
A single oral capsule taken once daily. No injections, gels, or in-office visits required.
Once-daily oral dosing
References
- Wiehle RD, et al. Enclomiphene citrate stimulates testosterone production while preventing oligospermia: a randomized phase II clinical trial comparing topical testosterone. Fertil Steril. 2014;102(3):720-727.
- Kim ED, McCullough A, Kaminetsky J. Oral enclomiphene citrate raises testosterone and preserves sperm counts in obese hypogonadal men, unlike topical testosterone. BJU Int. 2016;117(4):677-685.
- Kaminetsky J, Werner M, Fontenot G, Wiehle RD. Oral enclomiphene citrate stimulates the endogenous production of testosterone and sperm counts in men with low testosterone: comparison with testosterone gel. J Sex Med. 2013;10(6):1628-1635.
- Helo S, et al. Serum levels of enclomiphene and zuclomiphene in men with hypogonadism on long-term clomiphene citrate treatment. BJU Int. 2017;119(1):171-176.
Enclomiphene or Traditional TRT
Injected or topical testosterone replaces the hormone from outside. Enclomiphene prompts your body to make more of its own. That difference is why it is studied to preserve fertility.
| Enclomiphene | Traditional TRT | |
|---|---|---|
| How it works | Signals your body to make its own testosterone | Replaces testosterone from an external source |
| Fertility markers | Studied to preserve LH, FSH, and sperm | Can suppress natural production and sperm |
| Format | One daily oral capsule | Injections, gels, or creams |
| Sperm counts in trials | Stayed in the normal range | Fell with testosterone gel |
| Monitoring | Provider-reviewed labs | Provider-reviewed labs |
| Best for | Men who want higher T while keeping fertility options open | Men who need direct hormone replacement |
What to expect
Your testosterone is rechecked by bloodwork over the first one to three months, and your provider tunes the dose to your labs.
Week 1 to 2
Start your capsule
Begin your once-daily dose after your provider confirms your prescription.
Week 3 to 4
Settle in
Continue daily dosing. Message your care team anytime with questions.
Week 6 to 8
Recheck labs
Follow-up bloodwork measures how your testosterone, LH, and FSH have responded.
Ongoing
Provider tunes your dose
Your provider adjusts the dose to your labs and goals, with unlimited follow-ups.
Safety and side effects
Needs provider review and baseline labs, and it is not right for everyone. Enclomiphene is not FDA-approved; FDA lists enclomiphene citrate in Category 1 of the bulk drug substances nominated for 503A compounding, which means it is under evaluation, not approved (FDA list updated May 14, 2026). Its parent drug, clomiphene, carries a label warning about blurred vision, spots or flashes, so report any vision change right away. Tell your provider about any hormone-sensitive conditions or fertility plans.
Common
- Headache
- Nausea
- Hot flashes
- Mild mood changes
Less common
- Changes in vision or blurriness
- Acne or oily skin
- Changes in libido
Seek care
- Sudden vision loss
- Signs of a blood clot such as swelling, chest pain, or shortness of breath
This is not a complete list of side effects. Enclomiphene requires baseline and follow-up labs and is not for use by women or anyone under 18. Tell your provider about every medication you take and any hormone-sensitive condition or fertility plans before starting.
Frequently asked questions
Does enclomiphene work?
In randomized trials in men with secondary hypogonadism, enclomiphene raised total testosterone along with LH and FSH, and sperm counts stayed in the normal range, while testosterone gel lowered sperm counts (Wiehle et al., 2014; Kim et al., 2016). Your provider confirms your own response with follow-up bloodwork.
What are the side effects of enclomiphene?
In two phase II trials with results posted on ClinicalTrials.gov, the most frequent side effects in the enclomiphene groups were nausea and diarrhea, each reported by one or two men per group, and no serious adverse events were reported in those groups (NCT01270841, NCT01386606). These were short trials, so long-term safety is not established. Clomiphene's label warns about blurred vision, spots or flashes, so tell your provider about any vision change.
What dose of enclomiphene is used?
Trials tested 6.25 mg, 12.5 mg and 25 mg once daily (NCT01386606, NCT01270841). This plan is compounded in those strengths, and your provider chooses your dose from your labs and adjusts it after follow-up bloodwork.
What is the difference between enclomiphene and Clomid?
Clomid (clomiphene citrate) is an FDA-approved fertility drug for women, and its label describes it as a mixture of two isomers with 30% to 50% zuclomiphene; the rest is enclomiphene. Enclomiphene is the trans isomer on its own. In men taking clomiphene long term, zuclomiphene built up to about 20 times the level of enclomiphene in the blood (Helo et al., 2017), which is one reason researchers have studied enclomiphene by itself.
Is enclomiphene a steroid?
No. It is not testosterone or an anabolic steroid. It stimulates your own natural production upstream.
How is this different from TRT?
Injected testosterone replaces the hormone and can lower your own production. Enclomiphene works upstream to raise your natural testosterone, which is why it is studied to preserve fertility markers.
Will I need bloodwork?
Yes. A provider reviews baseline labs before prescribing and rechecks your testosterone over the first one to three months to tune your dose.
Other hormone therapy options
Everyday essentials for your routine.
No prescription needed. Dietary supplements for the daily habits around your care, sold separately from prescription treatment. Ask your provider before adding one to your routine.
Dietary supplements, not medications. These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Approval is never automatic.
An independent US-licensed clinician reviews every request. If they decide the treatment is not right for you, you get a full refund for the medication.
Choose a planNo insurance required
Prescriptions are filled by a US-licensed pharmacy and shipped free, in discreet packaging, on every plan.
LegitScript-certified · Cert 50087439
Compounded medications are prepared by a US-licensed pharmacy and are not reviewed by the FDA for safety or effectiveness. Products are dispensed only after a licensed provider determines they are appropriate. Information here is educational and is not a substitute for medical advice.