- Concentration
- estriol 0.3%, vitamin C 5% and hydrolyzed hyaluronic acid 0.5%
- Unit
- 30 gram container
- Category
- Prescription Skincare
Common questions
Is this the same as oral estradiol?
What ingredients and strengths are included?
Can I subscribe or make a one-time purchase?
Estriol / Vitamin C / Hyaluronic Acid
Three ingredients, one skin-focused formula.
Estriol 0.3%, vitamin C 5% and hydrolyzed hyaluronic acid 0.5%.
- Estriol 0.3%
- Vitamin C 5%
- Hydrolyzed hyaluronic acid 0.5%
What's Included
- ✓Medication and supplies
- ✓Provider visit and unlimited follow-ups
- ✓Free expedited shipping
Pause, change, or cancel anytime from your account.
How Would You Like To Pay?
Choose Your Plan
1-Month Plan
$158- $158 Billed Today
- Then $158 Every Month
- Cancel Anytime
Or pay with
$158 billed today, then every month until canceled.
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Your provider confirms the strength and dose after intake. Payment does not guarantee a prescription.
HealthRX.com verified facts
Estriol / Vitamin C / Hyaluronic Acid online: price and access
Estriol / Vitamin C / Hyaluronic Acid starts at $158 per month on monthly plan; the lowest checkout charge is $158 (billed monthly). A prescription is never guaranteed. A licensed provider reviews each request before a pharmacy can dispense treatment.
Catalog verified October 3, 2026. Source: HealthRX.com checkout catalog and refund policy. Monthly equivalent divides the discounted plan charge by the number of months; checkout may collect a multi-month total.
A straightforward path to care
Select your plan
Choose your treatment options and complete secure checkout. Then complete the online health intake.
Provider review
A licensed provider reviews your health history and determines whether this treatment is appropriate for you.
Ships to your door
If prescribed, a US-licensed pharmacy prepares and ships your medication.
Ongoing support
Contact the care team with questions about your treatment or order.
Estriol 0.3%
A topical estrogen ingredient, distinct from the oral and patch hormone options.
Vitamin C 5%
A skin-focused ingredient studied in topical photoaging formulations.
Hydrolyzed hyaluronic acid 0.5%
A moisture-focused ingredient included alongside estriol and vitamin C.
Three ingredients together
One blended topical formula instead of three separate products.
About Estriol / Vitamin C / Hyaluronic Acid
This topical formula pairs estriol with vitamin C and hydrolyzed hyaluronic acid. Estriol is an estrogen ingredient studied in aging skin; vitamin C has its own topical skin research, while hyaluronic acid brings a moisture-focused component. The three ingredients come together in one formulation.
- Estriol 0.3%
- Vitamin C 5%
- Hydrolyzed hyaluronic acid 0.5%
Estriol
The estrogen component has been studied in topical aging-skin care.
Vitamin C
The formula includes vitamin C alongside the estriol component.
Hyaluronic acid
The third ingredient adds a moisture-focused component.
What the research shows
The references below study topical estrogen and vitamin C formulations separately. The estrogen study compared estriol 0.3% with estradiol 0.01%; the vitamin C study evaluated a separate cream.
59 participants
The topical-estrogen study compared two estrogen formulations over six months.
Schmidt et al., 1996
6 months
A separate randomized vitamin C cream study assessed photoaged skin over six months.
Humbert et al., 2003
Estriol + Vitamin C + Hyaluronic Acid or Tretinoin + Niacinamide
Compare the ingredients and format before choosing your plan.
| Estriol + Vitamin C + Hyaluronic Acid | Tretinoin + Niacinamide | |
|---|---|---|
| Formula | Estriol / vitamin C / hyaluronic acid | Tretinoin / niacinamide / hyaluronic acid |
| Format | Topical cream | Topical cream |
| Ordering | Online plan selection | Online plan selection |
What to expect
The steps from choosing your plan to continuing your routine.
Getting started
Choose your plan
Compare the ingredients and the available purchase options.
After checkout
Follow your treatment plan
Use the instructions provided with your prescribed formulation.
Along the way
Keep in touch
Contact the existing care team with questions about your treatment or order.
Frequently asked questions
Which plan lengths can I choose?
How do I choose between similar formulations?
Other prescription skincare options
Approval is never automatic.
An independent US-licensed clinician reviews every request. If they decide the treatment is not right for you, you get a full refund for the medication.
Prescriptions are filled by a US-licensed pharmacy and shipped free, in discreet packaging, on every plan.
LegitScript-certified · Cert 50087439
Compounded medications are prepared by a US-licensed pharmacy and are not reviewed by the FDA for safety or effectiveness. Products are dispensed only after a licensed provider determines they are appropriate. Information here is educational and is not a substitute for medical advice.