Just three amino acids
Lys-Pro-Val, the last three amino acids of alpha-MSH, a hormone your body makes.
- By mouth or on the skinSupply
- KPV acetateStrength
- Provider reviewedBefore anything ships
The people pictured are models, not patients.
RxLongevity
KPV
KPV by prescription. Coming soon.
40,000+ products sold · LegitScript certified
KPV is a three-amino-acid peptide, the tail end of the hormone alpha-MSH. HHS opened it to US 503A pharmacies in October 2026, by mouth or on the skin only. Our pharmacy is adding it as a single-ingredient prescription. Join the list to be first.
- Coming soon
- No injections
- Provider reviewed
- Free to join the list
LegitScript certifiedCert. 50087439- US-licensed pharmacyPrepares every prescription
- Independent cliniciansUS-licensed, in your state
- 40,000+Products sold
- All 50 statesFree, discreet shipping
- No insurance requiredOne price, shown up front
Breakfast at home
KPV by prescription. Coming soon.
- 01Coming soon
- 02No injections
- 03Provider reviewed
- 04Free to join the list
The people pictured are models, not patients.
Why KPV
Studied in the gut
In mice, KPV in drinking water reduced colitis. In human gut cells it was taken up by the PepT1 transporter.
By mouth or on the skin
HHS's policy covers KPV taken by mouth or put on the skin, not injected. That is how ours will come.
First in line
Join the list and we will text and email you the day it is ready to order. Free, no payment now.
How we compare
KPV, without the waiting room.
HealthRX.comTypical in-person visit
Start online, no appointment or waiting roomBook, travel and wait
A US-licensed clinician reviews your history
Price shown before you startDepends on the visit and insurance
No insurance requiredOften billed through insurance
Delivered to your door in a plain boxPick up at the pharmacy
Full refund if you are not prescribedVisit fees usually apply either way
Understand your treatment
Three amino acids from a hormone you make.
KPV is the tail end of alpha-MSH, a hormone involved in skin color and inflammation signaling. Research has looked at it in the gut and skin. HHS covers KPV by mouth or on the skin only.
A closer look
Three amino acids from a hormone you make.
Lys-Pro-Val
PepT1
By mouth or on skin
Make a more informed choice
KPV vs. alpha-MSH
Alpha-MSH is a 13-amino-acid hormone. KPV is its last three amino acids. HHS's policy covers KPV acetate taken by mouth or applied to the skin, never injected.
A straightforward path to care
Join the list
Leave your email and mobile number. We tell you the day it is ready to order.
Provider review
The day our pharmacy can fill KPV as a single-ingredient prescription, you get a text and an email.
Ships to your door
Order online, do a short intake, and a US-licensed provider decides if KPV is right for you.
Ongoing support
A state-licensed US 503A pharmacy makes it for you by name and ships it free in plain packaging.
- Provider review
- An independent US-licensed clinician reviews every request.
- Free, discreet shipping
- Filled by a US-licensed pharmacy and shipped in discreet packaging.
- Not prescribed?
- You get a full refund for the medication.
About KPV
KPV is the tripeptide Lys-Pro-Val, the last three amino acids of alpha-MSH, a hormone your body makes. Research has looked at it in the gut and skin. In gut cells it is taken up by PepT1, a peptide transporter. Ours will be KPV acetate as the only active ingredient, taken by mouth or put on the skin, compounded by a US 503A pharmacy.
- Three amino acids: Lys-Pro-Val
- KPV acetate, the only active ingredient
- By mouth or on the skin, never injected
- Prescribed after a US-licensed provider review
Sequence: Lys-Pro-Val (HHS Appendix B, 2026).
Alpha-MSH
a 13-amino-acid hormone your body makes
Lys-Pro-Val
its last three amino acids, KPV
PepT1
the gut transporter that took KPV into cells in a lab study
A three-amino-acid peptide, coming by mouth or on the skin.
What the research shows
KPV research is mostly cell and mouse work. Here is what the record shows.
3
amino acids make up KPV: lysine, proline and valine.
HHS Appendix B, 2026
In mice
KPV given in drinking water reduced chemically induced colitis.
Dalmasso et al., Gastroenterology 2008
No needles
HHS's policy covers KPV by mouth or on the skin only.
HHS 503A peptide policy, 2026
HealthRX.com or Research-use sites
Two very different ways to get KPV
| HealthRX.com | Research-use sites | |
|---|---|---|
| Who makes it | A state-licensed US 503A pharmacy, from your prescription | Often overseas labs, sold as powder in a vial |
| Labeled for | You, by name, with your provider's directions | "Research use only. Not for human use." |
| Who checks it fits you | A US-licensed provider reviews your health history | No one |
| What is in it | KPV acetate, one ingredient | The seller's own claims |
| Questions later | Message your care team anytime | Seller support, if any |
| Price | Shown up front, full refund if not prescribed | Often less per vial, with no medical review |
What to expect
Here is what happens from joining the list to your first order.
Today
Join the list
Free. No payment and no intake yet.
Launch day
You hear first
We text and email you the moment it is ready to order.
Then
Order and do your intake
Choose a plan, then a short online health intake for a provider to review.
Within about a week
It arrives
If prescribed, the pharmacy ships it in plain packaging, with your directions on the label.
Safety and side effects
KPV is compounded by a US-licensed 503A pharmacy and is not FDA approved. FDA has not reviewed it for safety, effectiveness or quality, and human studies are small. A licensed provider reviews your health history and medicines before deciding whether to prescribe it. It is not for use during pregnancy or breastfeeding, or by anyone under 18. Report side effects to your provider, or to FDA MedWatch at 1-800-FDA-1088.
Common
- Stomach upset
- Skin irritation where a cream is applied
Less common
- Irritation that does not settle after a few days
Seek care
- Signs of an allergic reaction: hives, swelling of the face or throat, or trouble breathing
Human safety data for KPV are limited. Tell your provider about every medicine you take before starting. This is not a complete list of side effects.
Frequently asked questions
What does the research show?
In mice, KPV given in drinking water reduced colitis, and in human gut cells it was taken up by the PepT1 transporter (Dalmasso et al., 2008). Human studies are limited. Your provider will go through what is and is not known.
What will it cost?
We will show every price on this page before launch, with the online provider visit, the medication if prescribed and shipping included. Joining the list is free.
Who should not take KPV?
It is not for anyone pregnant, breastfeeding or under 18. Your provider reviews your health history and medicines before deciding.
Other longevity options
Everyday essentials for your routine.
No prescription needed. Dietary supplements for the daily habits around your care, sold separately from prescription treatment. Ask your provider before adding one to your routine.
Dietary supplements, not medications. These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Approval is never automatic.
An independent US-licensed clinician reviews every request. If they decide the treatment is not right for you, you get a full refund for the medication.
Get early accessNo insurance required
Prescriptions are filled by a US-licensed pharmacy and shipped free, in discreet packaging, on every plan.
LegitScript-certified · Cert 50087439
Compounded medications are prepared by a US-licensed pharmacy and are not reviewed by the FDA for safety or effectiveness. Products are dispensed only after a licensed provider determines they are appropriate. Information here is educational and is not a substitute for medical advice.