No needles
A nasal spray form of NAD+ for people who would rather not inject.
- One month supplySupply
- 3 strengthsSet by your provider
- Provider reviewedBefore anything ships
The people pictured are models, not patients.
RxLongevity
NAD+ Nasal Spray
Your NAD+, without the needle.
40,000+ products sold · LegitScript certified
A nasal spray form of NAD+, compounded by a licensed pharmacy for people who'd rather avoid injections. Human data on this delivery method is limited, and your provider reviews your file before confirming it's appropriate for you.
- No needles
- Skips the gut
- Compact and portable
- Provider-reviewed
What's Included
- ✓Medication and supplies
- ✓Provider visit and unlimited follow-ups
- ✓Free expedited shipping
Pause, change, or cancel anytime from your account.
This medication is prepared by a licensed compounding pharmacy. Compounded medications are not reviewed by the FDA for safety or effectiveness and are dispensed only after a licensed provider determines they are appropriate for you.
How Would You Like To Pay?
Choose Your Plan
1-Month Plan
$134- $134 Billed Today
- Then $134 Every Month
- Cancel Anytime
Or pay with
$134 billed today, then every month until canceled.
Not prescribed? Full refund.
After checkout you complete a short medical review in your member portal, and a US-licensed provider reviews it before your NAD+ nasal spray ships.
Full refund if not prescribed Free, discreet shipping Cancel anytime
Order today and here is what happens next
- TodayChoose a plan, then a short online intake
- Within about 24 hoursA US-licensed provider reviews your request
- Ships in 3 to 5 daysEstimated ship date, if prescribed
- Full refund
- If a provider does not prescribe it
- Licensed clinicians
- An independent US-licensed clinician reviews every request
- US-licensed pharmacy
- Prepares and ships your prescription
- Discreet delivery
- Plain, unmarked packaging
Common questions
Is NAD+ nasal spray FDA-approved?
No. Like the injectable form, NAD+ nasal spray is not FDA-approved for any use. It is compounded by a licensed pharmacy and offered as an investigational wellness option. FDA lists NAD in Category 1 of the bulk drug substances nominated for 503A compounding, which means the agency is still evaluating it, not that it is approved.
How much does NAD+ nasal spray cost at HealthRX.com?
The plan selector on this page shows the current price of every plan before you pay, and longer plans cost less per month. Each plan includes the medication, the online provider visit with follow-up messages, and shipping. You pay cash, and insurance is not needed. If the provider decides it is not right for you, you get a full refund.
Does NAD+ nasal spray work?
Nobody has published a human study showing that nasal NAD+ improves energy, focus, sleep or ageing measures, or measuring how much of a nasal dose reaches the blood. Claims of those benefits go beyond the evidence. The research behind the nasal route is a rat stroke study (Ying et al., 2007), which cannot tell you what a human dose does.
LegitScript certifiedCert. 50087439- US-licensed pharmacyPrepares every prescription
- Independent cliniciansUS-licensed, in your state
- 40,000+Products sold
- All 50 statesFree, discreet shipping
- No insurance requiredOne price, shown up front
Workdays
Your NAD+, without the needle.
- 01No needles
- 02Skips the gut
- 03Compact and portable
- 04Provider-reviewed
The people pictured are models, not patients.
Why NAD+ Nasal Spray
Skips the gut
Delivered through your nose rather than swallowed, which avoids the poor oral absorption of NAD+ pills.
Compact and portable
A 15 mL bottle at 300 mg/mL that is easy to keep with you and use on the go.
A provider reviews first
A licensed physician (MD) reviews your completed intake and prescribes only if it fits, with real pricing shown up front and honest notes on the evidence.
How we compare
NAD+ Nasal Spray, without the waiting room.
HealthRX.comTypical in-person visit
Start online, no appointment or waiting roomBook, travel and wait
A US-licensed clinician reviews your history
Price shown before you startDepends on the visit and insurance
No insurance requiredOften billed through insurance
Delivered to your door in a plain boxPick up at the pharmacy
Full refund if you are not prescribedVisit fees usually apply either way
Understand your treatment
NAD in a different delivery format.
This product presents NAD in a nasal formulation. The ingredient is a coenzyme involved in cellular metabolism and electron-transfer reactions; the format is what distinguishes this listing from NAD injection. A clear comparison also separates NAD itself from precursor ingredients such as NR and NMN. Comparing named molecules and delivery routes is more informative than grouping every NAD-related product under an energy label.
A closer look
NAD in a different delivery format.
NAD coenzyme
Cellular metabolism
Nasal formulation
Make a more informed choice
Nasal NAD vs. injectable NAD
The catalog offers separate delivery formats. A nasal formula and an injection have different administration routines. Neither listing is the same product as an oral precursor supplement.
A straightforward path to care
Select your plan
Choose your treatment options and complete secure checkout. Then complete the online health intake.
Provider review
A licensed physician (MD) reviews your completed intake and prescribes the nasal spray only if it is appropriate.
Ships to your door
A US-licensed pharmacy compounds your nasal spray and ships it free in discreet packaging.
Ongoing support
Message your care team with questions and adjust your plan as needed.
- Provider review
- An independent US-licensed clinician reviews every request.
- Free, discreet shipping
- Filled by a US-licensed pharmacy and shipped in discreet packaging.
- Not prescribed?
- You get a full refund for the medication.
About NAD+ Nasal Spray
Like the injectable form, NAD+ nasal spray is built around the idea of raising NAD+ levels without relying on oral absorption, which breaks most of it down before it can be used. Instead, the nasal spray aims to reach the bloodstream through the nasal lining. We need to be very direct about the evidence gap here: there is no human pharmacokinetic data on this delivery method at all. What exists is a rat stroke model (Ying et al., 2007), not a human study, so we genuinely don't know how much NAD+ a human nasal dose actually delivers or how quickly. We offer it as an investigational wellness option, not a proven treatment.
- A non-invasive alternative to injection for people who prefer to avoid needles
- Avoids the poor oral absorption that limits NAD+ taken by mouth as a pill or capsule
- Investigational status and the human-data gap disclosed clearly, not glossed over
- Offered as a wellness option only, with expectations set by what's actually been studied
NAD+
is a coenzyme your cells use in energy metabolism
Nasal spray
delivers it across the lining of your nose instead of the gut
Cells
use NAD+ as a cofactor in everyday redox reactions
NAD+ is a coenzyme central to cell metabolism, delivered here as a nasal spray.
NAD+ Nasal Spray or NAD+ Injection
Two ways to take NAD+
| NAD+ Nasal Spray | NAD+ Injection | |
|---|---|---|
| Format | Nasal spray | Subcutaneous injection |
| Needles | No needles | A small injection each dose |
| Portability | Compact and easy to carry | Kept and given at home |
| Absorption | Absorbed across the nasal lining | Enters below the skin, skipping the gut |
| Human data | No human absorption data for this route yet | Limited human data |
| Best for | People who would rather skip needles | People who want the most direct route |
What to expect
Because there's no human absorption data, we can't tell you a reliable onset time or how much reaches your system, and we won't estimate one just to fill in the gap. What is documented, from the nasal delivery format generally, includes nasal irritation, rhinitis, and headache. If you want a format with some human data behind it, small studies have given NAD+ intravenously; nobody has published a human study of nasal NAD+.
Week 1
Start your spray
Begin using your nasal spray on the schedule your provider sets.
Week 2 to 4
Settle into the routine
Continue your regular use and message your care team anytime.
Month 2
Check in
Your provider reviews how you are doing and can adjust your plan.
Ongoing
Provider tunes your plan
Your provider tailors your plan to your goals, with unlimited follow-ups.
Safety and side effects
This product is compounded by a licensed pharmacy and is not FDA-approved. It has not undergone FDA review for safety or efficacy, and its use is investigational; human absorption data for this delivery method does not currently exist. FDA lists nicotinamide adenine dinucleotide (NAD) in Category 1 of the bulk drug substances nominated for 503A compounding, which means it is under evaluation, not approved (FDA list updated May 14, 2026). Your provider proceeds with extra caution in anyone with severe liver or kidney disease, an active infection, uncontrolled diabetes, or significant cardiovascular disease.
Common
- Nasal irritation or burning
- Runny or stuffy nose
- Sneezing
- Mild throat irritation
Less common
- Headache
- Nosebleed
- Altered sense of smell or taste
Seek care
- Allergic reaction such as rash, swelling, or trouble breathing
- Severe or lasting nosebleeds, stop and seek care
NAD+ nasal spray is compounded by a US-licensed pharmacy and prescribed off-label. There is no human pharmacokinetic data on this nasal route, so how much NAD+ your body absorbs this way is not established. It is not for use during pregnancy or by anyone under 18. Tell your provider about every medication you take before starting. This is not a complete list of side effects.
Frequently asked questions
How do you use NAD+ nasal spray?
Your provider sets how many sprays to use and how often after reviewing your intake, and your pharmacy label gives the instructions for your bottle. There is no established human dose for nasal NAD+, so follow your prescription rather than dosing guides found online.
Is there human research on NAD+ nasal spray?
Not yet. The only supporting data comes from a rat stroke model, not a human study, so there's no confirmed human pharmacokinetic data showing how much NAD+ actually reaches your bloodstream through this route or how fast. We think that gap is important enough to say outright rather than imply otherwise.
How is the nasal spray different from the NAD+ injection?
The injection goes under the skin and gives a measured dose each time. Small human studies have given NAD+ intravenously, though not under the skin. The nasal spray avoids needles entirely but has no human absorption data, only a rat stroke model. Your provider can help you weigh convenience against the evidence for each.
What side effects are reported with NAD+ nasal spray?
Reported effects associated with this nasal delivery format include nasal irritation, rhinitis, and headache. Because human efficacy and absorption data for this specific product don't yet exist, your provider focuses the conversation on these known local effects and on your overall health history before deciding whether it's appropriate for you.
Other longevity options
Everyday essentials for your routine.
No prescription needed. Dietary supplements for the daily habits around your care, sold separately from prescription treatment. Ask your provider before adding one to your routine.
Dietary supplements, not medications. These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Approval is never automatic.
An independent US-licensed clinician reviews every request. If they decide the treatment is not right for you, you get a full refund for the medication.
Choose a planNo insurance required
Prescriptions are filled by a US-licensed pharmacy and shipped free, in discreet packaging, on every plan.
LegitScript-certified · Cert 50087439
Compounded medications are prepared by a US-licensed pharmacy and are not reviewed by the FDA for safety or effectiveness. Products are dispensed only after a licensed provider determines they are appropriate. Information here is educational and is not a substitute for medical advice.