Salicylic acid 2%
An exfoliating ingredient included in the cream.
- 30 gram containerSupply
- 4 activesIn one formula
- Provider reviewedBefore anything ships
The people pictured are models, not patients.
RxPrescription Skincare
Salicylic Acid / Zinc Oxide / Niacinamide / Urea
Four ingredients in one topical cream.
40,000+ products sold · LegitScript certified
Salicylic acid 2%, zinc oxide 5%, niacinamide 8% and urea 2%. Meet the exfoliating, skin-conditioning and moisture-focused components.
Explore the ingredients and compare options →What's Included
- ✓Medication and supplies
- ✓Provider visit and unlimited follow-ups
- ✓Free expedited shipping
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1-Month Plan
$150- $150 Billed Today
- Then $150 Every Month
- Cancel Anytime
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$150 billed today, then every month until canceled.
Not prescribed? Full refund.
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Order today and here is what happens next
- TodayChoose a plan, then a short online intake
- Within about 24 hoursA US-licensed provider reviews your request
- Ships to your doorIf prescribed, in a plain box
- Full refund
- If a provider does not prescribe it
- Licensed clinicians
- An independent US-licensed clinician reviews every request
- US-licensed pharmacy
- Prepares and ships your prescription
- Discreet delivery
- Plain, unmarked packaging
Common questions
Is this the three-ingredient salicylic cream?
No. This formulation also contains urea 2%, alongside salicylic acid 2%, zinc oxide 5% and niacinamide 8%.
What ingredients and strengths are included?
Salicylic acid 2%, zinc oxide 5%, niacinamide 8% and urea 2%.
Can I subscribe or make a one-time purchase?
Yes. Choose Subscribe & Save or One-time purchase in the plan picker. The price and selected plan are displayed before checkout.
LegitScript certifiedCert. 50087439- US-licensed pharmacyPrepares every prescription
- Independent cliniciansUS-licensed, in your state
- 40,000+Products sold
- All 50 statesFree, discreet shipping
- No insurance requiredOne price, shown up front
Morning routine
Four ingredients in one topical cream.
- 01Salicylic acid 2%
- 02Zinc oxide 5%
- 03Niacinamide 8%
The people pictured are models, not patients.
Why Salicylic Acid / Zinc Oxide / Niacinamide / Urea
Zinc oxide 5%
The zinc ingredient in this formulation is specifically zinc oxide.
Niacinamide 8%
The formula includes vitamin B3 at the verified concentration.
Urea 2%
A fourth ingredient that separates this cream from the three-ingredient blend.
How we compare
Salicylic Acid / Zinc Oxide / Niacinamide / Urea, without the waiting room.
HealthRX.comTypical in-person visit
Start online, no appointment or waiting roomBook, travel and wait
A US-licensed clinician reviews your history
Price shown before you startDepends on the visit and insurance
No insurance requiredOften billed through insurance
Delivered to your door in a plain boxPick up at the pharmacy
Full refund if you are not prescribedVisit fees usually apply either way
Meet the formula
Exfoliation is only one part of this formula.
A product for blemish-prone skin can contain more than an exfoliating acid. This blend includes salicylic acid 2%, zinc oxide 5%, niacinamide 8% and urea 2%. Salicylic acid gives it a beta hydroxy acid component, while the other named ingredients bring different roles to the topical formula. Understanding those roles keeps the product comparison focused on the complete blend, rather than treating four ingredients as four exfoliants or assuming every acne-oriented cream is a retinoid.
01
Exfoliating component
Salicylic acid, a beta hydroxy acid
02
Skin-conditioning components
Zinc oxide and niacinamide
03
Moisture component
Urea, a water-binding ingredient
Inside the formula
The names on the label, explained.
2%
Salicylic acid
Salicylic acid is a beta hydroxy acid, commonly called a BHA. It is used in acne care for its exfoliating and comedolytic properties, which relate to the buildup of material in pores. It supplies the acid component in this blend. Its ingredient family differs from tretinoin, the retinoid found in other topical catalog products.
5%
Zinc oxide
Zinc oxide is the zinc ingredient named in this formula. It adds a skin-protectant ingredient to the blend, rather than another BHA. Its role is separate from salicylic acid’s exfoliation and urea’s moisture binding. The listed 5% identifies this component of the complete topical formulation.
8%
Niacinamide
Niacinamide is vitamin B3 in a form used in topical skincare. Research has examined skin appearance and barrier-related biology. It is a different ingredient from salicylic acid, even when both appear in the same skincare routine. The 8% figure identifies this blend’s niacinamide component, distinct from the concentrations in neighboring niacinamide formulas.
2%
Urea
Urea is a humectant that helps attract and retain water in the outer skin. Its concentration affects how a topical urea product is understood: moisture binding and stronger keratolytic formulations are separate contexts. Here the listed 2% provides the moisture-focused component of a multi-ingredient cream, alongside the BHA and the other named actives.
A closer look / 01
Pores and dryness can be separate parts of the same routine.
The appearance of pores, the number of visible blemishes and areas that feel dry or rough tell you different things. An exfoliating ingredient addresses a different part of that picture from a humectant. Reading salicylic acid and urea separately helps explain why the blend includes both, and why this listing offers more information than a simple “2% acid” label.
This is also a useful way to inventory existing products. Identify any acids, retinoids and hydrating ingredients already in the routine. That reveals overlapping ingredient roles and makes the comparison between a complete blend and individual products more concrete.
A closer look / 02
A BHA and a retinoid use different ingredient pathways.
Salicylic acid is an exfoliating BHA. Tretinoin is a retinoid that acts through retinoic-acid receptors. A formula based on one is therefore different from a formula based on the other, even when both are discussed for blemish-prone skin. The supporting ingredients also differ across catalog blends, so the full ingredient list is the best place to start the comparison.
A closer look / 03
Keep the research matched to the formulation.
Published salicylic-acid studies include particular creams and combination regimens. Urea research includes hydration and skin-barrier measurements using its own concentrations. Those studies explain why the ingredient families are of interest. This listing combines four specified actives, which is a separate formulation from the individual study products. Following the ingredient and study design makes the research links more informative than transferring one study’s result to every cream.
Make an informed comparison
Compare the actual ingredients and formats.
Compare both the central active and the supporting ingredients. This formula combines a BHA with zinc oxide, niacinamide and urea. Retinoid and pigment-focused alternatives have different ingredient maps, even when a shared ingredient such as niacinamide appears in both.
| Option | Ingredient identity | What distinguishes it |
|---|---|---|
| This blend | Salicylic acid / zinc oxide / niacinamide / urea | BHA with skin-conditioning and moisture components |
| Tretinoin / Niacinamide / Vitamin C | Tretinoin / niacinamide / vitamin C | Retinoid-centered topical blend |
| Hydroquinone / Kojic Acid / Niacinamide | Hydroquinone / kojic acid / niacinamide | Pigment-focused topical blend |
The useful details
A few questions worth answering.
Are all four ingredients exfoliants?
They belong to different groups. Salicylic acid is the BHA; urea contributes moisture binding at the listed concentration; niacinamide is vitamin B3; zinc oxide supplies a separate skin-protectant ingredient. Understanding those roles explains the complete product more clearly than counting actives.
What would I observe over time?
Separate visible blemishes, rough areas and the feel of dryness. Note the other active products in your routine and use the same lighting for photos. This keeps different skin observations distinct and gives follow-up conversations more useful detail than one overall complexion rating.
Explore the ingredient research
Follow the sources.
See the available product options.
View optionsA straightforward path to care
Select your plan
Choose your treatment options and complete secure checkout. Then complete the online health intake.
Provider review
A licensed provider reviews your health history and determines whether this treatment is appropriate for you.
Ships to your door
If prescribed, a US-licensed pharmacy prepares and ships your medication.
Ongoing support
Contact the care team with questions about your treatment or order.
- Provider review
- An independent US-licensed clinician reviews every request.
- Free, discreet shipping
- Filled by a US-licensed pharmacy and shipped in discreet packaging.
- Not prescribed?
- You get a full refund for the medication.
Formula details, research & comparisons
About Salicylic Acid / Zinc Oxide / Niacinamide / Urea
This cream brings salicylic acid, zinc oxide, niacinamide and urea into one formula. Its ingredient list combines an exfoliating acid with zinc oxide, vitamin B3 and urea. The urea component distinguishes it from the separate three-ingredient salicylic acid blend.
- Salicylic acid 2%
- Zinc oxide 5%
- Niacinamide 8%
Salicylic acid
The exfoliating acid component.
Zinc oxide and niacinamide
Two additional ingredients in the same cream.
Urea
The fourth component in this specific formulation.
What the research shows
The cited niacinamide study examined a 5% facial formulation over 12 weeks. This cream contains niacinamide at 8% alongside three other ingredients.
12 weeks
The separate 5% niacinamide trial followed skin-appearance changes over 12 weeks.
Bissett et al., 2005
Salicylic Acid + Zinc + Niacinamide + Urea or Tretinoin Cream
Compare the ingredients and format before choosing your plan.
| Salicylic Acid + Zinc + Niacinamide + Urea | Tretinoin Cream | |
|---|---|---|
| Formula | Salicylic acid / zinc oxide / niacinamide / urea | Tretinoin retinoid |
| Format | Topical cream | Topical cream |
| Ordering | Online plan selection | Online plan selection |
What to expect
The steps from choosing your plan to continuing your routine.
Getting started
Choose your plan
Compare the ingredients and the available purchase options.
After checkout
Follow your treatment plan
Use the instructions provided with your prescribed formulation.
Along the way
Keep in touch
Contact the existing care team with questions about your treatment or order.
HealthRX.com verified facts
Salicylic Acid / Zinc Oxide / Niacinamide / Urea online: price and access
Salicylic Acid / Zinc Oxide / Niacinamide / Urea starts at $150 per month on monthly plan; the lowest checkout charge is $150 (billed monthly). A prescription is never guaranteed. A licensed provider reviews each request before a pharmacy can dispense treatment.
Catalog verified October 3, 2026. Source: HealthRX.com checkout catalog and refund policy. Monthly equivalent divides the discounted plan charge by the number of months; checkout may collect a multi-month total.
Frequently asked questions
Which plan lengths can I choose?
This cream currently has a one-month option.
How do I choose between similar formulations?
Compare the ingredient lists and discuss your skin goals with your care team.
Other prescription skincare options
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Hydroquinone 8% Cream
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Dapsone Acne Cream
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Learn MoreAdd to your daily routine.
No prescription needed. Dietary supplements to keep alongside your skin care routine, sold separately from prescription treatment. Ask your provider before adding one to your routine.
Dietary supplements, not medications. These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Approval is never automatic.
An independent US-licensed clinician reviews every request. If they decide the treatment is not right for you, you get a full refund for the medication.
Choose a planNo insurance required
Prescriptions are filled by a US-licensed pharmacy and shipped free, in discreet packaging, on every plan.
LegitScript-certified · Cert 50087439
Compounded medications are prepared by a US-licensed pharmacy and are not reviewed by the FDA for safety or effectiveness. Products are dispensed only after a licensed provider determines they are appropriate. Information here is educational and is not a substitute for medical advice.