Three ingredients
Tadalafil, oxytocin and PT-141 in the verified nasal formulation.
- 10 MilliliterSupply
- 6 strengthsSet by your provider
- Provider reviewedBefore anything ships
The people pictured are models, not patients.
RxSexual Health
Tadalafil / Oxytocin / PT-141 Nasal Spray
Three ingredients in a nasal format.
40,000+ products sold · LegitScript certified
Tadalafil 50 mg/mL, oxytocin 600 IU/mL and PT-141 2.5 mg/mL in one nasal blend. Meet each ingredient and compare the formulation with tablets and single-ingredient products.
Explore the ingredients and compare options →What's Included
- ✓Medication and supplies
- ✓Provider visit and unlimited follow-ups
- ✓Free expedited shipping
Pause, change, or cancel anytime from your account.
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1-Month Plan
$218- $218 Billed Today
- Then $218 Every Month
- Cancel Anytime
Or pay with
$218 billed today, then every month until canceled.
Not prescribed? Full refund.
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Order today and here is what happens next
- TodayChoose a plan, then a short online intake
- Within about 24 hoursA US-licensed provider reviews your request
- Ships to your doorIf prescribed, in a plain box
- Full refund
- If a provider does not prescribe it
- Licensed clinicians
- An independent US-licensed clinician reviews every request
- US-licensed pharmacy
- Prepares and ships your prescription
- Discreet delivery
- Plain, unmarked packaging
Common questions
Is this the same as a tadalafil tablet?
No. This is a nasal formulation with tadalafil, oxytocin and PT-141. Tadalafil tablets contain a different ingredient combination and use the oral route.
What ingredients and strengths are included?
Tadalafil 50 mg/mL, oxytocin 600 IU/mL and PT-141 2.5 mg/mL.
Can I subscribe or make a one-time purchase?
Yes. Choose Subscribe & Save or One-time purchase in the plan picker. The price and selected plan are displayed before checkout.
LegitScript certifiedCert. 50087439- US-licensed pharmacyPrepares every prescription
- Independent cliniciansUS-licensed, in your state
- 40,000+Products sold
- All 50 statesFree, discreet shipping
- No insurance requiredOne price, shown up front
Evenings together
Three ingredients in a nasal format.
- 01Three ingredients
- 02A nasal format
- 03Four plan lengths
The people pictured are models, not patients.
Why Tadalafil / Oxytocin / PT-141 Nasal Spray
A nasal format
A different route from oral tablets and standalone injections.
Four plan lengths
One-, three-, six- and twelve-month options are available.
Flexible purchase options
Use the existing subscription or one-time purchase selector to choose how you order.
How we compare
Tadalafil / Oxytocin / PT-141 Nasal Spray, without the waiting room.
HealthRX.comTypical in-person visit
Start online, no appointment or waiting roomBook, travel and wait
A US-licensed clinician reviews your history
Price shown before you startDepends on the visit and insurance
No insurance requiredOften billed through insurance
Delivered to your door in a plain boxPick up at the pharmacy
Full refund if you are not prescribedVisit fees usually apply either way
Meet the formula
Three ingredients. Three distinct pathways.
This formula combines a PDE5 inhibitor with two peptides in a nasal format. Tadalafil supplies the PDE5 component, oxytocin supplies oxytocin-receptor signaling, and PT-141 supplies melanocortin-receptor activity. The useful explanation is the role of each ingredient, rather than treating “three in one” as a measure of strength. These are different pharmacologic families brought into one formulation, with concentrations that identify this specific product.
01
PDE5 pathway
Tadalafil and the cGMP blood-flow signal
02
Oxytocin pathway
Peptide signaling at oxytocin receptors
03
Melanocortin pathway
PT-141, also called bremelanotide
Inside the formula
The names on the label, explained.
50 mg/mL
Tadalafil
Tadalafil inhibits phosphodiesterase type 5, or PDE5. This enzyme breaks down cGMP, a messenger involved in smooth-muscle relaxation during an erectile response. Tadalafil is also available in separate oral products. Here it is one ingredient in a nasal blend, so the ingredient name identifies the molecule while the complete listing identifies the formulation.
600 IU/mL
Oxytocin
Oxytocin is a peptide hormone with roles in social and reproductive signaling. It acts through oxytocin receptors, a different target from PDE5. Its inclusion gives the blend an ingredient from that signaling family. The oxytocin concentration here also differs from the oxytocin-only nasal listing, which contains 100 IU/mL.
2.5 mg/mL
PT-141
PT-141 is also called bremelanotide. It is a melanocortin-receptor agonist, meaning it activates receptors in that family. Published bremelanotide research includes a subcutaneous injectable formulation. The molecule helps explain this ingredient’s receptor target; the nasal route helps explain why this is a distinct product from an injectable PT-141 listing.
A closer look / 01
Read the units ingredient by ingredient.
Tadalafil and PT-141 are listed in milligrams per milliliter. Oxytocin is listed in international units per milliliter. Milligrams describe mass; international units describe biological activity using an ingredient-specific standard. The three numbers therefore cannot be added into a single potency score. Each concentration tells you something about its own ingredient within the blend.
A concentration also differs from the amount delivered on an occasion. The volume delivered and the prescribed product instructions complete that picture. The catalog’s three concentration values identify the formula being compared, without requiring you to treat a spray as an oral tablet or transfer an injectable schedule to it.
A closer look / 02
Why the delivery route belongs in the comparison.
A nasal spray, swallowed tablet and injection are separate formulations. Delivery affects the context in which an ingredient is used and studied. For example, tadalafil’s oral-product research and bremelanotide’s injectable-product research explain their ingredient families, while this listing combines them with oxytocin in a nasal product. Comparing the actual route alongside the active ingredients makes the product choice much more concrete.
A closer look / 03
Make sense of the research by following the target.
PDE5 research concerns a blood-flow signaling pathway. Oxytocin studies have explored sexual function and partner interaction. Bremelanotide studies have explored sexual desire using their own patient populations and endpoints. Reading these as three research strands gives each ingredient a clear identity. It also avoids treating separate studies as a clinical trial of this finished three-ingredient nasal formulation.
Make an informed comparison
Compare the actual ingredients and formats.
Start with the full formula and the route. A tadalafil tablet offers one ingredient in an oral product. An oxytocin-only spray offers one peptide in a nasal product. This listing combines three active ingredients across three receptor or enzyme targets.
| Option | Ingredient identity | What distinguishes it |
|---|---|---|
| This nasal blend | Tadalafil / oxytocin / PT-141 | Three pathways; nasal formulation |
| Oxytocin Nasal Spray | Oxytocin 100 IU/mL | Single-ingredient nasal formulation |
| Tadalafil | Tadalafil | Single-ingredient oral tablet |
| PT-141 | Bremelanotide | Injectable peptide formulation |
The useful details
A few questions worth answering.
Does a blend mean three separate effects are guaranteed?
The ingredient list describes the design of the formulation. Understanding each target explains why the ingredients are different. A particular experience or result is a separate question from identifying those targets, and studies of individual products use their own routes, doses and outcomes.
Is this the same formulation as TEMPO?
TEMPO contains apomorphine, sildenafil, tadalafil and vardenafil in a sublingual format. This nasal blend contains tadalafil, oxytocin and PT-141. Tadalafil is the shared ingredient; the other ingredients, pharmacologic groups and delivery format differ.
Explore the ingredient research
Follow the sources.
See the available product options.
View optionsA straightforward path to care
Select your plan
Choose your treatment options and complete secure checkout. Then complete the online health intake.
Provider review
A licensed provider reviews your health history and determines whether this treatment is appropriate for you.
Ships to your door
If prescribed, a US-licensed pharmacy prepares and ships your medication.
Ongoing support
Contact the care team with questions about your treatment or order.
- Provider review
- An independent US-licensed clinician reviews every request.
- Free, discreet shipping
- Filled by a US-licensed pharmacy and shipped in discreet packaging.
- Not prescribed?
- You get a full refund for the medication.
Formula details, research & comparisons
About Tadalafil / Oxytocin / PT-141 Nasal Spray
This nasal spray combines tadalafil, oxytocin and PT-141 in a single formulation. It provides a different route and ingredient combination from oral tadalafil or a standalone PT-141 injection. Choose a one-, three-, six- or twelve-month plan using the same plan picker as the other HealthRX.com treatments.
- Three ingredients
- A nasal format
- Four plan lengths
Tadalafil
One of three ingredients in the nasal formulation.
Oxytocin
The second ingredient, specified in IU/mL.
PT-141
The third ingredient, also known as bremelanotide.
What the research shows
Oxytocin has been studied separately through the nasal route. The trial below evaluated oxytocin alone in healthy men, rather than this three-ingredient combination.
103 participants
This randomized study evaluated intranasal oxytocin in healthy men.
Walch et al., 2001
No detectable difference
The study found no detectable effect on ejaculation time or seminal parameters.
Walch et al., 2001
Tadalafil + Oxytocin + PT-141 Nasal Spray or Tadalafil Tablets
Compare the ingredients and format before choosing your plan.
| Tadalafil + Oxytocin + PT-141 Nasal Spray | Tadalafil Tablets | |
|---|---|---|
| Formula | Tadalafil / oxytocin / PT-141 nasal spray | Tadalafil oral tablet |
| Format | Nasal spray | Oral tablet |
| Ordering | Online plan selection | Online plan selection |
What to expect
The steps from choosing your plan to continuing your routine.
Getting started
Choose your plan
Compare the ingredients and the available purchase options.
After checkout
Follow your treatment plan
Use the instructions provided with your prescribed formulation.
Along the way
Keep in touch
Contact the existing care team with questions about your treatment or order.
HealthRX.com verified facts
Tadalafil / Oxytocin / PT-141 Nasal Spray online: price and access
Tadalafil / Oxytocin / PT-141 Nasal Spray starts at $110 per month on 12-month plan; the lowest checkout charge is $218 (billed monthly). A prescription is never guaranteed. A licensed provider reviews each request before a pharmacy can dispense treatment.
Catalog verified October 3, 2026. Source: HealthRX.com checkout catalog and refund policy. Monthly equivalent divides the discounted plan charge by the number of months; checkout may collect a multi-month total.
Frequently asked questions
Which plan lengths can I choose?
One-, three-, six- and twelve-month plans are available in the plan picker.
How do I choose between similar formulations?
Compare the ingredients, route and plan options with your care team.
Other sexual health options
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Aminophylline / Ergoloid / Pentoxifylline / Sildenafil
From $143/mo
Learn More
Oxytocin Nasal Spray
Oxytocin 100 IU/mL
From $165/mo
Learn More
TEMPO 4-in-1
Apomorphine / Sildenafil / Tadalafil / Vardenafil
From $88/mo
Learn More
Sildenafil
50mg / 100mg
From $35/moabout $6/dose
Learn MoreApproval is never automatic.
An independent US-licensed clinician reviews every request. If they decide the treatment is not right for you, you get a full refund for the medication.
Choose a planNo insurance required
Prescriptions are filled by a US-licensed pharmacy and shipped free, in discreet packaging, on every plan.
LegitScript-certified · Cert 50087439
Compounded medications are prepared by a US-licensed pharmacy and are not reviewed by the FDA for safety or effectiveness. Products are dispensed only after a licensed provider determines they are appropriate. Information here is educational and is not a substitute for medical advice.