- Concentration
- tretinoin 0.05%, niacinamide 5% and vitamin C 5%
- Unit
- 30 gram container
- Category
- Prescription Skincare
Common questions
How is this different from the existing tretinoin and niacinamide cream?
What ingredients and strengths are included?
Can I subscribe or make a one-time purchase?
Tretinoin / Niacinamide / Vitamin C
A retinoid blend with vitamin C.
Tretinoin 0.05%, niacinamide 5% and vitamin C 5%.
- Tretinoin 0.05%
- Niacinamide 5%
- Vitamin C 5%
What's Included
- ✓Medication and supplies
- ✓Provider visit and unlimited follow-ups
- ✓Free expedited shipping
Pause, change, or cancel anytime from your account.
How Would You Like To Pay?
Choose Your Plan
1-Month Plan
$150- $150 Billed Today
- Then $150 Every Month
- Cancel Anytime
Or pay with
$150 billed today, then every month until canceled.
By completing your order, you agree to the HealthRX.com Terms & Conditions and Privacy Policy, and confirm you are 18 or older.
Your provider confirms the strength and dose after intake. Payment does not guarantee a prescription.
HealthRX.com verified facts
Tretinoin / Niacinamide / Vitamin C online: price and access
Tretinoin / Niacinamide / Vitamin C starts at $150 per month on monthly plan; the lowest checkout charge is $150 (billed monthly). A prescription is never guaranteed. A licensed provider reviews each request before a pharmacy can dispense treatment.
Catalog verified October 3, 2026. Source: HealthRX.com checkout catalog and refund policy. Monthly equivalent divides the discounted plan charge by the number of months; checkout may collect a multi-month total.
A straightforward path to care
Select your plan
Choose your treatment options and complete secure checkout. Then complete the online health intake.
Provider review
A licensed provider reviews your health history and determines whether this treatment is appropriate for you.
Ships to your door
If prescribed, a US-licensed pharmacy prepares and ships your medication.
Ongoing support
Contact the care team with questions about your treatment or order.
Tretinoin 0.05%
A defined retinoid concentration in the verified formulation.
Niacinamide 5%
The same vitamin B3 concentration evaluated in a 12-week skin-appearance trial.
Vitamin C 5%
The third ingredient in this blend, replacing the hyaluronic acid found in another option.
One combined formula
Three named ingredients and concentrations, shown together before you choose a plan.
About Tretinoin / Niacinamide / Vitamin C
This formula pairs tretinoin with niacinamide and vitamin C in one topical blend. Tretinoin is the retinoid component, niacinamide is vitamin B3, and vitamin C adds a different third ingredient from the hyaluronic acid in the existing tretinoin and niacinamide cream.
- Tretinoin 0.05%
- Niacinamide 5%
- Vitamin C 5%
Tretinoin
The retinoid component in the topical formula.
Niacinamide
Vitamin B3 is paired with the retinoid.
Vitamin C
Completes this three-ingredient formulation.
What the research shows
Niacinamide and vitamin C have been evaluated in separate skin-appearance trials. The references below cover those studied formulations.
50 participants
A separate study evaluated 5% niacinamide over 12 weeks.
Bissett et al., 2005
6 months
A separate vitamin C cream trial followed photoaged skin over six months.
Humbert et al., 2003
Tretinoin + Niacinamide + Vitamin C or Tretinoin + Niacinamide
Compare the ingredients and format before choosing your plan.
| Tretinoin + Niacinamide + Vitamin C | Tretinoin + Niacinamide | |
|---|---|---|
| Formula | Tretinoin / niacinamide / vitamin C | Tretinoin / niacinamide / hyaluronic acid |
| Format | Topical cream | Topical cream |
| Ordering | Online plan selection | Online plan selection |
What to expect
The steps from choosing your plan to continuing your routine.
Getting started
Choose your plan
Compare the ingredients and the available purchase options.
After checkout
Follow your treatment plan
Use the instructions provided with your prescribed formulation.
Along the way
Keep in touch
Contact the existing care team with questions about your treatment or order.
Frequently asked questions
Which plan lengths can I choose?
How do I choose between similar formulations?
Other prescription skincare options
Approval is never automatic.
An independent US-licensed clinician reviews every request. If they decide the treatment is not right for you, you get a full refund for the medication.
Prescriptions are filled by a US-licensed pharmacy and shipped free, in discreet packaging, on every plan.
LegitScript-certified · Cert 50087439
Compounded medications are prepared by a US-licensed pharmacy and are not reviewed by the FDA for safety or effectiveness. Products are dispensed only after a licensed provider determines they are appropriate. Information here is educational and is not a substitute for medical advice.