Has Joe Rogan confirmed using TRT?

Yes. Rogan has publicly discussed his testosterone replacement therapy use on The Joe Rogan Experience for over a decade, including references to injection-based testosterone, blood monitoring, and physician supervision.

What other substances has Joe Rogan publicly discussed using?

Rogan has confirmed use of HGH and has publicly discussed BPC-157, NAD+ supplementation, and other peptides. He has also discussed vitamin IV drips, sauna protocols, and various recovery modalities on his podcast.

Has Dwayne Johnson confirmed TRT use?

Johnson confirmed using steroids as a teenager in a 2009 interview. He has not publicly confirmed current testosterone replacement therapy or HGH use as an adult. Media speculation exists, but the HealthRX Medical Team categorizes his current status as not publicly confirmed.

Is TRT safe for men over 40?

The 2023 TRAVERSE trial, the largest randomized TRT safety study, found no increased cardiovascular risk in men with hypogonadism. TRT does carry risks including erythrocytosis, fertility suppression, and potential worsening of sleep apnea. It should be prescribed only after confirmed low testosterone levels and a clinical evaluation by a qualified physician.

Are the peptides Joe Rogan discusses FDA-approved?

BPC-157, ipamorelin, and similar peptides Rogan has discussed are not FDA-approved for any indication. They are sold through compounding pharmacies or research chemical suppliers. The FDA has issued warnings about unapproved peptide products. NAD+ precursors like NMN are sold as dietary supplements but lack large-scale clinical trial data for anti-aging claims.

Joe Rogan Compared to Other Public TRT Figures

By HealthRX Medical Team

Published May 25, 2026Updated May 25, 2026Last reviewed May 25, 2026

Joe Rogan's TRT Timeline: A Public Record

Joe Rogan first discussed his use of testosterone replacement therapy on The Joe Rogan Experience in the early 2010s and has revisited the topic in dozens of episodes since. Unlike most celebrity health disclosures, which arrive as isolated magazine quotes or damage-control statements, Rogan's TRT discussion is ongoing, detailed, and voluntary. He has described receiving testosterone via injection, discussed dose adjustments with guests, and referenced routine blood work monitoring.

Rogan has also publicly discussed adjacent protocols. He has confirmed use of human growth hormone (HGH) and has talked at length about peptides including BPC-157 and NAD+ supplementation. He has hosted physicians and researchers specializing in hormone optimization and longevity medicine, including Dr. Andrew Huberman, Dr. Peter Attia, and Dr. Mark Gordon, turning his podcast into a de facto public education channel on male hormone therapy.

His confirmed TRT use is not tied to a single medical event or crisis. Rogan has framed it as a proactive decision made in his 40s to maintain energy, body composition, and recovery capacity as he aged. This framing matters clinically because it mirrors the most common real-world TRT patient profile: men aged 40 to 60 seeking optimization rather than treating classical hypogonadism.

How Other Celebrities Have Gone Public With TRT

To understand what makes Rogan's disclosure pattern unusual, it helps to compare it against the broader record of celebrity TRT admissions.

Sylvester Stallone was caught by Australian customs in 2007 with vials of Jintropin (somatropin), a synthetic HGH. He later confirmed using testosterone and HGH for age-related recovery, telling Time magazine, "Everyone over 40 years old would be wise to investigate it." His disclosure was reactive, prompted by a legal incident, not voluntary.

Robbie Williams publicly confirmed TRT use in a 2023 interview, describing it as part of managing energy and mental health in his late 40s. His disclosure was a single public statement without the sustained, repeated discussion Rogan provides.

Joe Manganiello has spoken openly about fitness protocols and hinted at medically supervised hormone optimization, though he has not confirmed TRT use in the explicit terms Rogan has. His case remains publicly speculated rather than confirmed.

Dwayne "The Rock" Johnson admitted to using steroids as a teenager in a 2009 interview but has not publicly confirmed current TRT or HGH use. Media speculation about ongoing use is widespread, but Johnson has not made an on-the-record confirmation of adult hormone therapy. The HealthRX Medical Team categorizes his current status as not publicly confirmed.

Vince McMahon was named in a federal steroid distribution investigation in the early 1990s and later testified about personal steroid use. His disclosure was compelled by legal proceedings, not voluntary.

At a glance

Joe Rogan: Confirmed TRT, confirmed HGH, confirmed peptide use. Voluntary, ongoing, detailed public disclosure spanning 10+ years.
Sylvester Stallone: Confirmed TRT and HGH. Disclosure triggered by 2007 customs incident. Limited follow-up discussion.
Robbie Williams: Confirmed TRT. Single public statement in 2023.
Dwayne Johnson: Confirmed past teenage steroid use. Current TRT/HGH status not publicly confirmed.
Joe Manganiello: Speculated. No explicit public confirmation of TRT.
Vince McMahon: Confirmed past steroid use. Disclosure compelled by federal investigation.

What the Disclosure Patterns Reveal

Three distinct patterns emerge from this record. First, most celebrity TRT disclosures are reactive. They follow a customs seizure, a tabloid leak, or a legal proceeding. Rogan is the outlier: his disclosure is proactive and sustained. Second, almost no public figure provides dosing details, bloodwork discussion, or ongoing updates. Rogan does all three, albeit informally on his podcast rather than in a clinical publication. Third, the gap between what is publicly confirmed and what is widely speculated is enormous. The HealthRX Medical Team estimates that the number of male celebrities using some form of testosterone or growth hormone therapy far exceeds the number who have acknowledged it publicly.

This matters for patients. Celebrity silence creates an information vacuum that is filled by gym-culture speculation and underground dosing guides. When a figure like Rogan discusses TRT openly, with references to physician oversight and bloodwork, it creates a more accurate (if still incomplete) public model of what supervised testosterone therapy actually looks like.

Clinical Context: TRT in Men Over 40

Testosterone levels in men decline at a rate of approximately 1-2% per year after age 30. The Endocrine Society defines male hypogonadism as a total testosterone level below 300 ng/dL combined with symptoms such as fatigue, reduced libido, decreased muscle mass, or depressed mood. Their 2018 clinical practice guideline recommends TRT only for men with consistently low levels confirmed by at least two morning measurements, paired with clinical symptoms.

Standard TRT protocols for confirmed hypogonadism include:

Testosterone cypionate or enanthate: 100-200 mg intramuscular injection every 1-2 weeks
Testosterone gel (1-1.62%): 50-100 mg applied daily to shoulders or upper arms
Testosterone pellets (Testopel): 150-450 mg subcutaneous implants every 3-6 months

The TRAVERSE trial, published in the New England Journal of Medicine in 2023, followed 5,246 men aged 45 to 80 with hypogonadism and established cardiovascular disease or high cardiovascular risk. The trial found that testosterone replacement did not increase the incidence of major adverse cardiac events compared to placebo, addressing a longstanding safety concern. This was the largest randomized TRT safety trial to date.

Common side effects include erythrocytosis (elevated red blood cell count, requiring monitoring of hematocrit levels), acne, sleep apnea worsening, and suppression of endogenous gonadotropins, which can cause testicular atrophy and reduced fertility. Men considering future fertility should discuss these risks before starting therapy. The FDA requires a black box warning on testosterone products noting the difference between age-related testosterone decline and pathological hypogonadism.

The Peptide and HGH Layer

Rogan's public protocol goes beyond testosterone alone. He has discussed using HGH and several peptides on his podcast. BPC-157 (Body Protection Compound-157) is a synthetic peptide derived from a gastric protein that has shown wound-healing and anti-inflammatory properties in animal models, though no large-scale human clinical trials have been completed. The FDA has warned consumers about unapproved peptide products sold without regulatory oversight.

Growth hormone use in adults without documented GH deficiency is not FDA-approved and carries risks including joint pain, insulin resistance, carpal tunnel syndrome, and a theoretical concern for accelerating occult malignancies. NAD+ precursors (such as NMN and NR) are commercially available as supplements, and while preclinical data on their role in cellular metabolism is promising, clinical evidence for anti-aging outcomes in humans remains limited.

The HealthRX Medical Team notes that Rogan's public discussion of these compounds gives them a level of cultural legitimacy that outpaces their clinical evidence base. Listeners should distinguish between "a public figure reports using this" and "controlled trials support this for your situation."

The HealthRX Medical Team Take

Rogan's record is genuinely unusual. No other public figure has maintained this level of sustained, voluntary disclosure about hormone therapy. That openness has real value: it normalizes physician-supervised TRT, encourages bloodwork monitoring, and reframes testosterone therapy as a medical decision rather than a bodybuilding secret.

The risk is context collapse. Rogan is a wealthy, medically supervised individual with access to concierge physicians, frequent lab testing, and a recovery-oriented lifestyle (sauna, cold plunge, rigorous training). His results and risk profile are not transferable to a 45-year-old with untreated sleep apnea and no physician oversight who orders testosterone from an online clinic after hearing a podcast clip.

The HealthRX Medical Team recommends that any man considering TRT:

Obtain at least two fasting morning testosterone measurements confirming levels below 300 ng/dL before starting therapy.
Discuss fertility preservation strategies if future children are desired, as exogenous testosterone suppresses spermatogenesis.
Establish baseline hematocrit, PSA, and lipid panels, with monitoring every 6 to 12 months on therapy.
Treat modifiable causes of low testosterone first, including obesity, sleep apnea, opioid use, and excessive alcohol consumption, before assuming TRT is necessary.

Celebrity disclosures are data points, not prescriptions. Rogan's record is the most transparent in this category, but transparency about personal use is not the same as individualized medical guidance.

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