Dayvigo (Lemborexant) Storage, Stability & Shelf Life

Where to find storage directions for Dayvigo

Dayvigo is an oral tablet containing lemborexant [1]. The storage directions and expiration date that apply to a prescription are the ones printed on its carton and pharmacy label. A specific temperature range, container requirement, light-protection instruction or shelf-life period is not stated on this page, so those details should be read from the packaging.

Taking the tablet

The label says the recommended dose is 5 mg no more than once per night, immediately before going to bed, with at least 7 hours remaining before the planned time of awakening. It says the dose may be increased to a maximum of 10 mg based on response and tolerability, and that time to sleep onset may be delayed if the tablet is taken with or soon after a meal [1].

How Dayvigo works

The label says lemborexant is presumed to work by antagonizing orexin receptors OX1R and OX2R. This blocks the wake-promoting neuropeptides orexin A and orexin B and is thought to suppress wake drive [1]. It is not a benzodiazepine or a Z-drug such as zolpidem, which act on GABA-A receptors.

Regulatory status

The label states that Dayvigo contains lemborexant, a Schedule IV controlled substance [1]. It carries no boxed warning, and narcolepsy is its only contraindication [1]. The controlled-substance schedule is separate from the storage directions printed on the packaging.