24 source-based articles maintained by the HealthRX.com Editorial Team.
Showing 24 of 24 clinical reviews.
When is it safe to restart sildenafil after a heart attack, stroke, surgery, or serious infection? Board-certified physicians explain the evidence, timing, and dose adjustments.
A physician-reviewed deep dive into sildenafil's effects on skeletal muscle, exercise capacity, and emerging preservation strategies. Covers PDE5 inhibition, blood flow, mitochondrial signaling, clinical trials, and practical dosing context.
A physician-reviewed deep dive into sildenafil's effects on renal hemodynamics, diabetic nephropathy, AKI risk, and drug interactions, with primary-literature citations throughout.
A physician-reviewed, GRADE-graded breakdown of sildenafil's clinical evidence for erectile dysfunction, covering landmark trials, effect sizes, guideline recommendations, and practical dosing.
A clinical, week-by-week guide to sildenafil's onset, dose titration, side effects, and what changes you should notice in your first 30 days on Viagra, reviewed by board-certified physicians.
A clinician-reviewed look at whether sildenafil (Viagra) affects appetite, hunger, or food cravings, covering the pharmacology, trial data, patient reports, and what to do if you notice changes.
Sildenafil (Viagra) pharmacokinetics change significantly after Roux-en-Y gastric bypass and sleeve gastrectomy. Learn how altered absorption, faster Cmax, and drug, drug interactions affect dosing, safety, and clinical outcomes after weight-loss surgery.
A clinician-level review of sildenafil (Viagra) use in autoimmune and inflammatory conditions, covering pharmacology, drug interactions, disease-specific guidance, and safety data from primary literature.
A physician-reviewed deep dive into sildenafil's effects on bone mineral density, osteoblast signaling via PDE5 inhibition, and what the clinical evidence means for patients on long-term Viagra therapy.
A physician-reviewed deep dive into sildenafil's effects on cognition, cerebral blood flow, dementia risk, and brain health. Covers PDE5 inhibition mechanisms, clinical trial data, and practical prescribing considerations.
A physician-reviewed analysis of every major epidemiological signal linking sildenafil (Viagra) to cancer risk, including melanoma, prostate cancer, and the proposed PDE5 mechanism. Includes trial data, FDA communications, and a clinical decision framework.
A clinical deep-dive into sildenafil's long-term cardiovascular effects, covering PDE5 inhibitor mechanisms, mortality data, drug interactions, and who should avoid use. prepared by the HealthRX.com Editorial Team.
A clinical deep-dive into the documented hair and skin effects of sildenafil (Viagra), including flushing, rashes, alopecia signals, and what the primary literature actually says.
A clinician-level review of how sildenafil (Viagra) is metabolized by the liver, what hepatic impairment means for dosing, and which lab changes to monitor.
A physician-reviewed deep dive into sildenafil pharmacokinetics, PDE5 inhibition, thermogenic signaling, and what current evidence says about Viagra and metabolic rate in humans.
A clinical review of sildenafil microdosing protocols, including daily low-dose regimens, pharmacokinetic rationale, and evidence from key trials. Reviewed by board-certified physicians.
Sildenafil stopped working or never worked well? This MD-level guide covers every evidence-based reason for Viagra plateau and non-response, with specific doses, trials, and a step-by-step troubleshooting protocol.
A physician-reviewed guide to the sildenafil pre-surgery hold window: why anesthesiologists require it, exactly how long to stop Viagra before an operation, and what happens if the drug is still on board during general or neuraxial anesthesia.
Does stopping sildenafil cause rebound ED, withdrawal, or worsening erectile function? Board-reviewed clinical breakdown of the evidence, mechanisms, and what to do next.
A physician-reviewed guide to how temperature, altitude, cardiovascular demand, and seasonal activity patterns affect sildenafil (Viagra) dosing, safety, and efficacy throughout the year.
A physician-reviewed, evidence-based breakdown of how sildenafil (Viagra) affects sexual function, covering mechanism, efficacy data from landmark trials, dosing, safety, and who responds best.
A clinician-level review of how sildenafil (Viagra) affects REM sleep, slow-wave sleep, nocturnal penile tumescence, and overnight oxygen saturation, with primary-literature citations and dosing guidance.
How to time sildenafil (Viagra) doses when crossing time zones, managing jet lag, altitude, and travel-related factors that affect PDE5 inhibitor pharmacokinetics. Physician-reviewed protocols with primary-source citations.
A clinician-level review of how sildenafil (Viagra) affects mood, anxiety, depression, and psychological well-being in men with erectile dysfunction, with primary-literature citations throughout.