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Enclomiphene
A US-licensed compounding pharmacy cleanroom
  • LegitScript Certified
  • US-licensed pharmacy
  • Ships in 3 to 5 days
Concentration
Enclomiphene 6.25 / 12.5 / 25 mg
Purity
Provider reviewed
Unit
60 capsules
Category
Hormone Therapy

Common questions

Enclomiphene is an oral medication that signals your body to make more of its own testosterone, instead of replacing it the way injections do.

Enclomiphene

Your own testosterone, prompted, not replaced.

Enclomiphene · Provider-guided hormone support

  • Raises your own T
  • Oral capsule
  • Fertility-preserving
  • Provider-titrated
Personalized plan match

Find the plan that fits you.

Answer three quick questions to match your priorities and budget. Get your recommendation and free treatment guide by text. No card to start.

Plans from$165/monthSee your exact matched price before checkout
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Purchase type

Save 10% today and on every refill. Auto-renews at your selected cadence, pause or cancel anytime.

Cadence

Enclomiphene$206 billed monthly

Strength set by your provider. They confirm the right strength and dose after reviewing your required post-purchase intake.

Payment does not guarantee a prescription. Complete the required pharmacist intake after purchase.

Free provider visitFree discreet shippingPause or cancel anytime

What's included

  • Medication and supplies
  • Provider visit and unlimited follow-ups
  • Free expedited shipping

Pause, change, or cancel anytime from your account.

After checkout you complete a short medical review in your member portal, and a US-licensed provider reviews it before anything ships.

Raises your own testosterone

Works upstream to stimulate your body's natural production, rather than replacing the hormone from outside.

One daily capsule

No injections, gels, or needles. A single oral capsule taken once a day.

Studied to preserve fertility

Unlike testosterone replacement, it is studied to maintain the LH, FSH, and sperm markers tied to fertility.

A provider reviews your labs

A US-licensed provider reads your bloodwork first and prescribes only if it fits. Real pricing, shown up front.

About Enclomiphene

Enclomiphene works upstream. It signals your pituitary to release more LH and FSH, which tells your body to make more of its own testosterone, instead of replacing it the way injections do. It is a once-daily capsule, studied to preserve fertility markers. Your provider reviews your labs first, and the pharmacy compounds and ships your dose.

  • Raises your own testosterone, not a replacement
  • Oral capsule, no injections
  • Studied to preserve fertility markers versus TRT
  • Provider reviews your labs first, real pricing up front

Enclomiphene is the trans-isomer of clomiphene, a selective estrogen receptor modulator that raises LH and FSH. Compounded by a US-licensed pharmacy.

  1. Enclomiphene

    blocks the estrogen receptor at the pituitary

  2. Pituitary gland

    releases more LH and FSH

  3. Testes

    produce more of your own testosterone

Testosterone rises while fertility markers are preserved.

How it signals your body, the HPT axis

How to get it

A US-licensed compounding pharmacy cleanroom
  1. Today

    Take the quiz and labs

    Answer a few questions about your health and complete the recommended bloodwork.

  2. Next

    A provider reviews

    A US-licensed provider reviews your testosterone and history, then prescribes if it is appropriate.

  3. 3 to 5 days

    The pharmacy ships

    A US-licensed pharmacy compounds your dose and ships it free in discreet packaging.

  4. Ongoing

    Follow-up labs

    Repeat bloodwork tracks your response, and your provider tunes the dose to your labs.

What the research shows

Enclomiphene has been evaluated in randomized clinical trials in men with low testosterone. Here is what that research found.

Normal range

In randomized phase II trials, enclomiphene raised morning total testosterone back into the normal range in men with secondary hypogonadism.

Wiehle et al., Fertil Steril 2014; Kim et al., BJU Int 2016

Sperm preserved

Enclomiphene maintained sperm concentration and raised LH and FSH, where topical testosterone lowered them in the same trials.

Kim et al., BJU Int 2016

1x / day

A single oral capsule taken once daily. No injections, gels, or in-office visits required.

Once-daily oral dosing

References

  1. Wiehle RD, et al. Enclomiphene citrate stimulates testosterone production while preventing oligospermia: a randomized phase II clinical trial comparing topical testosterone. Fertil Steril. 2014;102(3):720-727.
  2. Kim ED, McCullough A, Kaminetsky J. Oral enclomiphene citrate raises testosterone and preserves sperm counts in obese hypogonadal men, unlike topical testosterone. BJU Int. 2016;117(4):677-685.

Enclomiphene or Traditional TRT

Injected or topical testosterone replaces the hormone from outside. Enclomiphene prompts your body to make more of its own. That difference is why it is studied to preserve fertility.

EnclomipheneTraditional TRT
How it worksSignals your body to make its own testosteroneReplaces testosterone from an external source
Fertility markersStudied to preserve LH, FSH, and spermCan suppress natural production and sperm
FormatOne daily oral capsuleInjections, gels, or creams
Testicular functionMaintainedCan decrease over time
MonitoringProvider-reviewed labsProvider-reviewed labs
Best forMen who want higher T while keeping fertility options openMen who need direct hormone replacement

What to expect

Your testosterone is rechecked by bloodwork over the first one to three months, and your provider tunes the dose to your labs.

  1. Week 1 to 2

    Start your capsule

    Begin your once-daily dose after your provider confirms your prescription.

  2. Week 3 to 4

    Settle in

    Continue daily dosing. Message your care team anytime with questions.

  3. Week 6 to 8

    Recheck labs

    Follow-up bloodwork measures how your testosterone, LH, and FSH have responded.

  4. Ongoing

    Provider tunes your dose

    Your provider adjusts the dose to your labs and goals, with unlimited follow-ups.

Safety and side effects

Needs provider review and baseline labs, and it is not right for everyone. Tell your provider about any hormone-sensitive conditions or fertility plans.

Common

  • Headache
  • Nausea
  • Hot flashes
  • Mild mood changes

Less common

  • Changes in vision or blurriness
  • Acne or oily skin
  • Changes in libido

Seek care

  • Sudden vision loss
  • Signs of a blood clot such as swelling, chest pain, or shortness of breath

This is not a complete list of side effects. Enclomiphene requires baseline and follow-up labs and is not for use by women or anyone under 18. Tell your provider about every medication you take and any hormone-sensitive condition or fertility plans before starting.

Frequently asked questions

Injected testosterone replaces the hormone and can lower your own production. Enclomiphene works upstream to raise your natural testosterone, which is why it is studied to preserve fertility markers.

Other hormone therapy options

Approval is never automatic.

An independent US-licensed clinician reviews every request. If they decide the treatment is not right for you, you get a full refund for the medication.

Check my eligibilityNo insurance required

Prescriptions are filled by a US-licensed pharmacy and shipped free, in discreet packaging, on every plan.

LegitScript-certified · Cert 50087439

Compounded medications are prepared by a US-licensed pharmacy and are not reviewed by the FDA for safety or effectiveness. Products are dispensed only after a licensed provider determines they are appropriate. Information here is educational and is not a substitute for medical advice.