Sexual Health
Tadalafil Daily
Your everyday option, at the strength that fits you.
Taken once a day, low-dose tadalafil keeps a steady level of medication in your system so timing around activity isn't necessary. Available in 2.5mg and 5mg, it's confirmed clinically appropriate for you by a board-certified physician before it ships.
Strength
Purchase type
Save 10% today and on every refill. Auto-renews at your selected cadence, pause or cancel anytime.
Cadence
Strength set by your provider. They confirm the right strength and dose for you during your online visit.
Only available if prescribed after an online consultation with a licensed provider.
What's included
- ✓Medication and supplies
- ✓Provider visit and unlimited follow-ups
- ✓Free expedited shipping
Pause, change, or cancel anytime from your account.
Always ready, no planning
A low daily dose keeps a steady level of tadalafil in your system, so you do not have to time anything around intimacy.
The lowest effective strengths
Daily dosing uses 2.5 mg or 5 mg, lower than the as-needed tablet, taken once every day.
The active ingredient in Cialis
Tadalafil is the same active ingredient found in branded Cialis for daily use, compounded by a US-licensed pharmacy.
A provider reviews you first
A US-licensed provider checks your health history and heart risks before prescribing. Real pricing, shown up front.
From quiz to your door
Daily tadalafil uses the same PDE5 mechanism as the as-needed doses, just at a much lower strength taken every day instead of before a single event. Because you take it continuously, tadalafil builds up to a steady level in your body over about five days, rather than rising and falling with a single dose, at either 2.5mg or 5mg. Like every PDE5 inhibitor, it requires sexual arousal to work; it doesn't create desire and won't produce an erection without stimulation, it simply keeps the response available at any time. 5mg delivers more active drug at that steady state than 2.5mg, for people who are sexually active more often or need a stronger response.
Answer a few health questions
Complete a short online visit about your health, heart history, and the medications you take.
A provider reviews
A US-licensed provider reviews your history and prescribes daily tadalafil if it is appropriate for you.
The pharmacy ships free
A US-licensed pharmacy compounds your dose and ships it free in discreet packaging.
Adjust with follow-ups
Message your care team anytime, and your provider can move you between 2.5 mg and 5 mg based on how you respond.
About Tadalafil Daily
- FDA-approved for daily use since 2008, with efficacy data extending out to three years
- No timing required around activity, since the medication stays at a steady level
- 5mg available in your file for a stronger response than 2.5mg, at the same steady-state timeline
- A milder side-effect profile than as-needed dosing for most people
- Best suited to those who are sexually active two or more times a week
What the studies show
Once-daily tadalafil has been evaluated in randomized, double-blind, placebo-controlled trials. Here is what that research found.
- Porst H, et al. Evaluation of the efficacy and safety of once-a-day dosing of tadalafil 5 mg and 10 mg in the treatment of erectile dysfunction: results of a multicenter, randomized, double-blind, placebo-controlled trial. Eur Urol. 2006;50(2):351-359.
- Rajfer J, et al. Tadalafil dosed once a day in men with erectile dysfunction: a randomized, double-blind, placebo-controlled study in the US. Int J Impot Res. 2007;19(1):95-103.
Two different approaches
Daily versus as needed
| Tadalafil daily | Tadalafil as needed | |
|---|---|---|
| How you take it | One low dose every day | A dose before intimacy |
| Spontaneity | ✓Always ready, no timing | Plan within a 36 hour window |
| Planning around sex | ✓None needed | Take ahead of time |
| Strength | 2.5 mg or 5 mg daily | 10 mg or 20 mg as needed |
| Best for | Frequent or spontaneous intimacy | Occasional, planned intimacy |
| Active ingredient | Same as branded Cialis for daily use | Same as branded Cialis |
Your first months
Daily tadalafil isn't meant to act quickly the way as-needed dosing does. Most people reach a steady state, and the full effect, within about five days of consistent use, whether they're taking 2.5mg or 5mg, though some notice a difference sooner and others take longer. Because the dose is lower and it's not building toward one peak, side effects tend to run milder than with as-needed tadalafil: headache, flushing, indigestion, and back pain, most of which ease within the first couple of weeks. Side effects can run slightly more noticeable at 5mg than at 2.5mg.
Start your daily dose
Begin one low-dose tablet each day once your provider confirms your prescription.
It builds up
Tadalafil accumulates to a steady level in your system over about five days of consistent use.
Steady state
You reach a steady baseline, so you are ready during arousal without timing a dose.
Provider tunes your dose
Your provider adjusts between 2.5 mg and 5 mg based on how you respond, with unlimited follow-ups.
What members say
“Taking a small dose every day means I never plan around it. After about a week it just felt normal and ready.”
“As-needed never fit my life. Daily was the switch that made it effortless, no timing at all.”
“My provider started me at 2.5 and moved me to 5 after follow-up. Pricing was upfront the whole way.”
Ratings and member reviews shown here are illustrative composites built from anonymized intake-to-outcome data; identifying details have been altered. Individual results vary. Compounded medications are not FDA-approved.
What to know about side effects
The same contraindications apply as with as-needed tadalafil: nitrates and alpha-blockers are both absolute, since either can drop your blood pressure to dangerous levels. Your provider also looks closely at kidney and liver function before starting daily dosing at either strength, since severe impairment in either organ changes how the medication is cleared and may call for a lower dose or a different option. If your provider decides daily tadalafil isn't clinically appropriate for you, you won't be charged for the medication.
Most common
- Headache
- Flushing
- Indigestion
- Back pain or muscle aches
Less common, talk to your provider
- Nasal congestion
- Changes in vision
- Dizziness
Rare but serious, seek care
- An erection lasting more than four hours, called priapism, which needs emergency care
- Sudden loss of vision or hearing, or chest pain, seek care right away
Frequently asked questions
Compounded medications are prepared by a US-licensed pharmacy and are not reviewed by the FDA for safety or effectiveness. Products are dispensed only after a licensed provider determines they are appropriate. Information here is educational and is not a substitute for medical advice.