AACE Obesity Pharmacotherapy: BMI 27+ With Comorbidity Rule
AACE, ADA, and Endocrine Society allow obesity drugs at BMI ≥30, or BMI ≥27 with a comorbidity. See how guidelines compare on thresholds and treatment eligibility.
11 source-based articles maintained by the HealthRX.com Editorial Team.

Showing 11 of 11 clinical reviews.
AACE, ADA, and Endocrine Society allow obesity drugs at BMI ≥30, or BMI ≥27 with a comorbidity. See how guidelines compare on thresholds and treatment eligibility.
Obesity (BMI ≥30) raises risk for 200+ conditions, most notably type 2 diabetes, heart disease, sleep apnea, MASLD, and osteoarthritis. See how they overlap.
A guide to exercise prescription for adults with obesity (BMI ≥30), covering AHA, ACSM, and Endocrine Society recommendations with specific protocols, doses, and trial data.
NIH first-line obesity treatment: a 500-750 kcal/day deficit plus 150-300 min/week exercise, yielding 5-10% weight loss in 6 months to cut cardiometabolic risk.
Evidence-based guide to caregiver support, family-based interventions, and practical resources for managing obesity (BMI ≥30), including behavioral strategies, medication awareness, and clinical guidelines from ADA, AACE, and the Endocrine Society.
A guideline-backed monitoring schedule for adults with obesity (BMI ≥30), covering lab work, vitals, metabolic panels, and follow-up intervals during pharmacotherapy and lifestyle intervention.
A clinical review of the most promising obesity trials, next-generation GLP-1 receptor agonists, combination therapies, and gene-based approaches reshaping how we treat BMI ≥30.
How genetics and family history influence obesity risk, BMI heritability, known gene variants like MC4R and FTO, and what this means for GLP-1 and other treatments.
Step-by-step obesity treatment algorithm organized by line of therapy, from lifestyle intervention through pharmacotherapy and metabolic surgery, based on ADA, AACE, and Endocrine Society guidelines.
How obesity management differs for older adults, adolescents, pregnant patients, and those with CKD, diabetes, or psychiatric conditions. Guideline-backed strategies with trial data.
Obesity raises depression risk 55%; depression raises obesity risk 58%. Learn what to monitor and how to treat both conditions together.