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12 clinically reviewed articles, written and peer-reviewed by the HealthRX.com Medical Team.
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Showing 12 of 12 clinical reviews.
A clinician-level review of pioglitazone use after bariatric surgery, covering pharmacokinetics, NASH evidence, insulin resistance, dosing, and safety in post-bariatric patients with type 2 diabetes or MASLD.
Read clinical reviewA physician-level review of how pioglitazone affects liver function, AST/ALT dynamics, NASH resolution data from PIVENS, and monitoring protocols for safe clinical use.
Read clinical reviewA physician-reviewed deep dive into how pioglitazone (Actos) affects mood, depression, anxiety, and cognition in patients with type 2 diabetes and NASH, with primary-literature citations throughout.
Read clinical reviewA physician-reviewed deep dive into pioglitazone microdosing protocols, low-dose evidence, NASH data from PIVENS, cardiovascular signals, and how clinicians are applying sub-standard doses off-label in 2024.
Read clinical reviewHow long before surgery should pioglitazone (Actos) be stopped? Board-reviewed guidance on the pre-surgery hold window, fluid-retention risks, anesthetic interactions, and restart protocols.
Read clinical reviewStopping pioglitazone (Actos) can trigger glycemic rebound, fluid shifts, NASH relapse, and cardiovascular changes. This MD-level guide covers the mechanisms, timelines, monitoring protocols, and tapering strategies backed by primary literature.
Read clinical reviewDoes pioglitazone protect the kidneys or harm them? This MD/PharmD-level review covers the clinical trial data, mechanisms, contraindications, and prescribing guidance for pioglitazone's renal effects in type 2 diabetes and NASH.
Read clinical reviewA clinician-level guide to how seasonal changes in temperature, diet, physical activity, and illness affect pioglitazone dosing, fluid retention, and glycemic control in type 2 diabetes and NASH.
Read clinical reviewA clinician-level review of how pioglitazone affects sexual function in men and women with type 2 diabetes, covering mechanisms, trial data, and clinical guidance.
Read clinical reviewA clinician-level review of how pioglitazone affects sleep architecture, REM sleep, sleep-disordered breathing, and overnight glucose regulation, with primary-literature citations and dosing guidance.
Read clinical reviewMD/PharmD-level guidance on traveling with pioglitazone: timezone dose-timing adjustments, flight hypoglycemia risk, storage requirements, customs documentation, and cross-border pharmacy access.
Read clinical reviewA physician-level guide to safely restarting pioglitazone after acute illness, covering hold criteria, timing, dose titration, monitoring, and the clinical evidence behind each recommendation.
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