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HealthRX.com · Printable medication review sheet

Switching between Zepbound pens and vials: training and supplies card

Fill this in when your prescription moves from a pen to a vial or the other way: the presentation, the volume per dose, the syringe you were given and who trained you, plus a four-week record after the switch and questions for the pharmacist.

Companion to “Zepbound Vials vs. Pen - Are They Equally Effective?” · healthrx.com/glp-1-faq/are-zepbound-vials-as-effective-as-the-pre-filled-pen-version-calibrate · Facts checked 2026-10-18

The switch

Presentation before
Presentation now
Strength (mg)
Volume per dose0.5 mL single-dose, 0.6 mL multi-dose
Syringes and needles suppliedsize and how many
Date of training, and who trained you

From the label

  • Vials need a syringe that can measure the dose, for example a 1 mL syringe for a 0.5 mL or 0.6 mL dose, and a new syringe and needle every time.[1]
  • Single-dose vials are thrown away after use, even with medicine left.[1]
  • Multi-dose vials and KwikPens are thrown away 30 days after first use or after 4 weekly doses.[1]
  • Single-dose pens and vials: up to 21 days in total out of the fridge, at no more than 86°F (30°C).[1]
  • When the presentation changes, the label calls for training on the new one.[1]

Before the first dose from the new presentation

  • Read the Instructions for Use that came with it
  • Found the 0.5 mL or 0.6 mL mark on your syringe
  • Checked the liquid is clear and colorless to slightly yellow
  • Know where used needles and syringes go
  • Picked a time when someone can answer questions

First four weeks after switching

WeekDatePresentation and strengthVolume drawnProblems drawing or injectingSide effects compared with before

For the pharmacist

  1. Does my plan cover the vial, the pen or both, and what will I pay for each?
  2. Which syringe should I use, and how do I get more?
  3. What do I do if I see air bubbles in the syringe?
  4. Who can check my technique if my weight trend changes after the switch?
Sources for the facts on this sheet
  1. Eli Lilly and Company, via DailyMed. Zepbound (tirzepatide) injection, for subcutaneous use: prescribing information, Medication Guide and Instructions for Use. Effective 2026-08-28. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=487cd7e7-434c-4925-99fa-aa80b1cc776b

This sheet records information for a conversation with your prescriber or pharmacist. It does not replace their instructions or the medication's prescribing information.