Back to the article

HealthRX.com · Printable side-effect diary

Zepbound injection site reaction diary

Use this diary to record each Zepbound injection, the body site used and any skin reaction after it. Bring the completed pages to your prescriber or pharmacist to review the pattern and plan questions.

Companion to “Diet and Lifestyle for Injection Site Reactions on Zepbound (Tirzepatide): What Actually Works” · healthrx.com/side-effects-zepbound-injection-site-reactions/dietary-strategies · Facts checked Nov 10, 2026

Injection record

Fill in one record for each new pen or when your injection routine changes.

Date of injectionWrite the day and month
Injection site usedAbdomen, thigh or back of upper arm
Who gave the injectionSelf or another person
Dose strength on the penCopy exactly what the pen label says
Pen or supplier changeNote any new pen, carton or pharmacy

Site rotation and reaction tracker

Record each injection and any bruising, redness, itching, pain or rash at the site over the following days.

DateSite usedReaction seenPain or itch notes

Before your visit

Gather these items before you speak with your prescriber or pharmacist.

  • Bring this diary and the Zepbound pen or carton
  • Note every injection site used since your last visit
  • Write each reaction in your own words and the date it began
  • List any new skin change that hurts when lightly touched
  • Confirm with your pharmacist which reactions you should report
  • Check with your prescriber how to handle swelling of the face, lips or throat

Questions to ask at your visit

  1. Which injection site reactions should I report to you, and how soon?
  2. What should I do if I notice swelling of the face, lips or throat?
  3. Are the reactions I am recording listed in the Zepbound label?
  4. Does rotating my injection sites change how I should record reactions?
  5. Could skin pain to light touch be linked to a recent dose change?
  6. Would checking for antibodies help explain repeated reactions?
  7. Who should I contact after hours about a bad reaction?

This sheet records information for a conversation with your prescriber or pharmacist. It does not replace their instructions or the medication's prescribing information.