- LegitScript Certified
- US-licensed pharmacy
- Ships in 3 to 5 days
Common questions
Sermorelin
Your pituitary, prompted, not replaced.
Sermorelin is compounded by a licensed pharmacy for off-label adult use, prescribed to stimulate your own pituitary rather than introduce growth hormone directly. Your provider reviews your file and confirms it's clinically appropriate for you.
- Prompts your own GH
- Preserves pulsatile release
- At-home injection
- Provider-set dose
Find the plan that fits you.
Answer three quick questions to match your priorities and budget. Get your recommendation and free treatment guide by text. No card to start.
Purchase type
Save 10% today and on every refill. Auto-renews at your selected cadence, pause or cancel anytime.
Cadence
Strength set by your provider. They confirm the right strength and dose after reviewing your required post-purchase intake.
Payment does not guarantee a prescription. Complete the required pharmacist intake after purchase.
What's included
- ✓Medication and supplies
- ✓Provider visit and unlimited follow-ups
- ✓Free expedited shipping
- ✓Injection home kit included
Pause, change, or cancel anytime from your account.
This medication is prepared by a licensed compounding pharmacy. Compounded medications are not reviewed by the FDA for safety or effectiveness and are dispensed only after a licensed provider determines they are appropriate for you.
After checkout you complete a short medical review in your member portal, and a US-licensed provider reviews it before your sermorelin ships.
Prompts your own growth hormone
Sermorelin signals your pituitary to release your own growth hormone, rather than replacing the hormone from outside.
Preserves your natural GH pulses
It works with your pituitary's own pulsatile release pattern, rather than adding a constant supply from outside.
A simple at-home injection
A small subcutaneous injection you give yourself at night, with an injection kit included.
A provider sets your dose
A US-licensed provider reviews your history and goals first and sets your strength, with real pricing shown up front.
About Sermorelin
Sermorelin is a GHRH(1-29) analog, a lab-made copy of the first 29 amino acids of your body's own growth hormone-releasing hormone. Instead of putting growth hormone into your system directly, the way an rhGH injection does, it tells your pituitary gland to make and release its own, so your natural feedback loop and pulsatile release pattern stay intact. We want to be clear about the distinction, because marketing in this category often blurs it: sermorelin is not HGH, and your provider won't describe it as an equivalent.
- Stimulates your own pituitary rather than introducing exogenous growth hormone
- Preserves the body's natural pulsatile GH release pattern, unlike direct rhGH
- Generally lower cost than synthetic HGH therapy
- Evidence disclosed honestly: mechanism is well established, long-term adult trial data is not
Sermorelin
binds GHRH receptors on your anterior pituitary
Pituitary gland
releases your own growth hormone in its natural pulses
Liver and tissues
respond to growth hormone as part of normal metabolism
Growth hormone is prompted from your own pituitary, not replaced from outside.
How to get it
Today
Take the quiz
Answer a few questions about your health, history, and goals in your member portal.
Next
A provider reviews
A US-licensed provider reviews your intake and prescribes sermorelin only if it is appropriate for you.
3 to 5 days
The pharmacy ships
A US-licensed pharmacy compounds your dose and ships it free in discreet packaging, with an injection kit.
Ongoing
Follow up anytime
Message your care team with questions, and your provider can adjust your dose over time.
Sermorelin or Direct HGH
Two different approaches
| Sermorelin | Direct HGH | |
|---|---|---|
| How it works | Signals your pituitary to release your own growth hormone | Replaces growth hormone from an external source |
| Release pattern | Preserves your natural pulsatile release | Adds a continuous outside supply |
| Feedback control | Stays subject to your body's own feedback loops | Bypasses your body's feedback loops |
| Format | Small at-home subcutaneous injection | Growth hormone injection |
| Oversight | Provider-reviewed, prescribed off-label | Provider-reviewed, tightly restricted |
| Best for | Adults who want to prompt their own GH pathway | Diagnosed adult growth hormone deficiency |
What to expect
After an injection, growth hormone spikes within roughly 30 to 60 minutes, then falls off again quickly. What most people are actually watching for, changes in body composition and energy, unfolds much more slowly: often starting around 4 to 12 weeks in and continuing to shift for up to 3 to 6 months of consistent use. Here's what we won't do: overstate the evidence behind that timeline. Sermorelin's only FDA approval, from 1990, covered diagnostic testing for growth hormone deficiency in children. Adult use is off-label, most of what we know comes from observational reports rather than large randomized trials, and your provider will tell you that directly rather than imply otherwise.
- Week 1 to 2
Start your injections
Begin your nightly subcutaneous dose after your provider confirms your prescription.
- Week 3 to 6
Settle into the routine
Continue your regular dosing and message your care team anytime with questions.
- Week 8 to 12
Check in with your provider
Your provider reviews how you are doing and can adjust your dose.
- Ongoing
Provider tunes your plan
Your provider tailors your dose to your response and goals, with unlimited follow-ups.
Safety and side effects
This product is compounded by a licensed pharmacy and is not FDA-approved. It has not undergone FDA review for safety or efficacy; its adult use is off-label. Sermorelin is absolutely contraindicated in anyone with active or recent cancer, since stimulating growth hormone release carries theoretical risk in that setting. Reported reactions include nausea, dizziness, flushing, headache, a mild uptick in blood sugar, and irritation or redness at the injection site. Your provider will also weigh retinopathy, any pituitary tumor history, thyroid conditions, and diabetes before confirming a prescription, since each changes how closely you'll need to be monitored.
Common
- Redness or swelling at the injection site
- Flushing
- Headache
- Mild dizziness
Less common
- Nausea
- Drowsiness
- Joint aches or swelling
Seek care
- Allergic reaction such as rash, swelling, or trouble breathing
- It is not for anyone with an active cancer, since growth hormone can affect existing tumors
Sermorelin is compounded by a US-licensed pharmacy and prescribed off-label. It is not for anyone with active cancer or malignancy, and it is not for use during pregnancy or by anyone under 18. Tell your provider about every medication you take and any history of cancer before starting. This is not a complete list of side effects.
Frequently asked questions
Other longevity options
Approval is never automatic.
An independent US-licensed clinician reviews every request. If they decide the treatment is not right for you, you get a full refund for the medication.
Prescriptions are filled by a US-licensed pharmacy and shipped free, in discreet packaging, on every plan.
LegitScript-certified · Cert 50087439
Compounded medications are prepared by a US-licensed pharmacy and are not reviewed by the FDA for safety or effectiveness. Products are dispensed only after a licensed provider determines they are appropriate. Information here is educational and is not a substitute for medical advice.