Longevity
Sermorelin
Your pituitary, prompted, not replaced.
Sermorelin is compounded by a licensed pharmacy for off-label adult use, prescribed to stimulate your own pituitary rather than introduce growth hormone directly. Your provider reviews your file and confirms it's clinically appropriate for you.
Purchase type
Save 10% today and on every refill. Auto-renews at your selected cadence, pause or cancel anytime.
Cadence
Strength set by your provider. They confirm the right strength and dose for you during your online visit.
Only available if prescribed after an online consultation with a licensed provider.
What's included
- ✓Medication and supplies
- ✓Provider visit and unlimited follow-ups
- ✓Free expedited shipping
- ✓Injection home kit included
Pause, change, or cancel anytime from your account.
This medication is prepared by a licensed compounding pharmacy. Compounded medications are not reviewed by the FDA for safety or effectiveness and are dispensed only after a licensed provider determines they are appropriate for you.
Prompts your own growth hormone
Sermorelin signals your pituitary to release your own growth hormone, rather than replacing the hormone from outside.
Preserves your natural GH pulses
It works with your pituitary's own pulsatile release pattern, rather than adding a constant supply from outside.
A simple at-home injection
A small subcutaneous injection you give yourself at night, with an injection kit included.
A provider sets your dose
A US-licensed provider reviews your history and goals first and sets your strength, with real pricing shown up front.
From quiz to your door
Sermorelin is a GHRH(1-29) analog, a lab-made copy of the first 29 amino acids of your body's own growth hormone-releasing hormone. Instead of putting growth hormone into your system directly, the way an rhGH injection does, it tells your pituitary gland to make and release its own, so your natural feedback loop and pulsatile release pattern stay intact. We want to be clear about the distinction, because marketing in this category often blurs it: sermorelin is not HGH, and your provider won't describe it as an equivalent.
Take the quiz
Answer a few questions about your health, history, and goals in your member portal.
A provider reviews
A US-licensed provider reviews your intake and prescribes sermorelin only if it is appropriate for you.
The pharmacy ships
A US-licensed pharmacy compounds your dose and ships it free in discreet packaging, with an injection kit.
Follow up anytime
Message your care team with questions, and your provider can adjust your dose over time.
About Sermorelin
- Stimulates your own pituitary rather than introducing exogenous growth hormone
- Preserves the body's natural pulsatile GH release pattern, unlike direct rhGH
- Generally lower cost than synthetic HGH therapy
- Evidence disclosed honestly: mechanism is well established, long-term adult trial data is not
Two different approaches
Two different approaches
| Sermorelin | Direct HGH | |
|---|---|---|
| How it works | ✓Signals your pituitary to release your own growth hormone | Replaces growth hormone from an external source |
| Release pattern | ✓Preserves your natural pulsatile release | Adds a continuous outside supply |
| Feedback control | ✓Stays subject to your body's own feedback loops | Bypasses your body's feedback loops |
| Format | Small at-home subcutaneous injection | Growth hormone injection |
| Oversight | Provider-reviewed, prescribed off-label | Provider-reviewed, tightly restricted |
| Best for | Adults who want to prompt their own GH pathway | Diagnosed adult growth hormone deficiency |
Your first months
After an injection, growth hormone spikes within roughly 30 to 60 minutes, then falls off again quickly. What most people are actually watching for, changes in body composition and energy, unfolds much more slowly: often starting around 4 to 12 weeks in and continuing to shift for up to 3 to 6 months of consistent use. Here's what we won't do: overstate the evidence behind that timeline. Sermorelin's only FDA approval, from 1990, covered diagnostic testing for growth hormone deficiency in children. Adult use is off-label, most of what we know comes from observational reports rather than large randomized trials, and your provider will tell you that directly rather than imply otherwise.
Start your injections
Begin your nightly subcutaneous dose after your provider confirms your prescription.
Settle into the routine
Continue your regular dosing and message your care team anytime with questions.
Check in with your provider
Your provider reviews how you are doing and can adjust your dose.
Provider tunes your plan
Your provider tailors your dose to your response and goals, with unlimited follow-ups.
What members say
“I liked that this works with my own pituitary instead of putting a hormone in from outside. A provider went through my history before anything shipped.”
“The nightly injection is smaller and simpler than I expected, and the kit made it easy to get started.”
“Pricing was on the page before I signed up and I could message the care team whenever I had a question.”
Ratings and member reviews shown here are illustrative composites built from anonymized intake-to-outcome data; identifying details have been altered. Individual results vary. Compounded medications are not FDA-approved.
What to know about side effects
This product is compounded by a licensed pharmacy and is not FDA-approved. It has not undergone FDA review for safety or efficacy; its adult use is off-label. Sermorelin is absolutely contraindicated in anyone with active or recent cancer, since stimulating growth hormone release carries theoretical risk in that setting. Reported reactions include nausea, dizziness, flushing, headache, a mild uptick in blood sugar, and irritation or redness at the injection site. Your provider will also weigh retinopathy, any pituitary tumor history, thyroid conditions, and diabetes before confirming a prescription, since each changes how closely you'll need to be monitored. If your provider decides sermorelin isn't clinically appropriate for you, you won't be charged for the medication.
Most common
- Redness or swelling at the injection site
- Flushing
- Headache
- Mild dizziness
Less common, talk to your provider
- Nausea
- Drowsiness
- Joint aches or swelling
Rare but serious, seek care
- Allergic reaction such as rash, swelling, or trouble breathing
- It is not for anyone with an active cancer, since growth hormone can affect existing tumors
Frequently asked questions
Compounded medications are prepared by a US-licensed pharmacy and are not reviewed by the FDA for safety or effectiveness. Products are dispensed only after a licensed provider determines they are appropriate. Information here is educational and is not a substitute for medical advice.