Longevity
Sermorelin
Your pituitary, prompted, not replaced.
Sermorelin is compounded by a licensed pharmacy for off-label adult use, prescribed to stimulate your own pituitary rather than introduce growth hormone directly. Your provider reviews your file and confirms it's clinically appropriate for you.
Purchase type
Save 10% today and on every refill. Auto-renews at your selected cadence, pause or cancel anytime.
Cadence
Only available if prescribed after an online consultation with a licensed provider.
What's included
- ✓Medication and supplies
- ✓Provider visit and unlimited follow-ups
- ✓Free expedited shipping
- ✓Injection home kit included
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This medication is prepared by a licensed compounding pharmacy. Compounded medications are not reviewed by the FDA for safety or effectiveness and are dispensed only after a licensed provider determines they are appropriate for you.
How it works
Sermorelin is a GHRH(1-29) analog, a lab-made copy of the first 29 amino acids of your body's own growth hormone-releasing hormone. Instead of putting growth hormone into your system directly, the way an rhGH injection does, it tells your pituitary gland to make and release its own, so your natural feedback loop and pulsatile release pattern stay intact. We want to be clear about the distinction, because marketing in this category often blurs it: sermorelin is not HGH, and your provider won't describe it as an equivalent.
What to expect
After an injection, growth hormone spikes within roughly 30 to 60 minutes, then falls off again quickly. What most people are actually watching for, changes in body composition and energy, unfolds much more slowly: often starting around 4 to 12 weeks in and continuing to shift for up to 3 to 6 months of consistent use. Here's what we won't do: overstate the evidence behind that timeline. Sermorelin's only FDA approval, from 1990, covered diagnostic testing for growth hormone deficiency in children. Adult use is off-label, most of what we know comes from observational reports rather than large randomized trials, and your provider will tell you that directly rather than imply otherwise.
- ✓Stimulates your own pituitary rather than introducing exogenous growth hormone
- ✓Preserves the body's natural pulsatile GH release pattern, unlike direct rhGH
- ✓Generally lower cost than synthetic HGH therapy
- ✓Evidence disclosed honestly: mechanism is well established, long-term adult trial data is not
Safety information
This product is compounded by a licensed pharmacy and is not FDA-approved. It has not undergone FDA review for safety or efficacy; its adult use is off-label. Sermorelin is absolutely contraindicated in anyone with active or recent cancer, since stimulating growth hormone release carries theoretical risk in that setting. Reported reactions include nausea, dizziness, flushing, headache, a mild uptick in blood sugar, and irritation or redness at the injection site. Your provider will also weigh retinopathy, any pituitary tumor history, thyroid conditions, and diabetes before confirming a prescription, since each changes how closely you'll need to be monitored. If your provider decides sermorelin isn't clinically appropriate for you, you won't be charged for the medication.
Frequently asked questions
Compounded medications are prepared by a US-licensed pharmacy and are not reviewed by the FDA for safety or effectiveness. Products are dispensed only after a licensed provider determines they are appropriate. Information here is educational and is not a substitute for medical advice.