Prompts your own growth hormone
Sermorelin signals your pituitary to release your own growth hormone, rather than replacing the hormone from outside.
- Monthly supplySupply
- SermorelinStrength
- Provider reviewedBefore anything ships
Illustrative photography with models, not patients.
RxLongevity
Sermorelin
Your pituitary, prompted, not replaced.
40,000+ products sold · LegitScript certified
Sermorelin is compounded by a licensed pharmacy for off-label adult use, prescribed to stimulate your own pituitary rather than introduce growth hormone directly. Your provider reviews your file and confirms it's clinically appropriate for you.
- Prompts your own GH
- Preserves pulsatile release
- At-home injection
- Provider-set dose
What's Included
- ✓Medication and supplies
- ✓Provider visit and unlimited follow-ups
- ✓Free expedited shipping
- ✓Injection home kit included
Pause, change, or cancel anytime from your account.
This medication is prepared by a licensed compounding pharmacy. Compounded medications are not reviewed by the FDA for safety or effectiveness and are dispensed only after a licensed provider determines they are appropriate for you.
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1-Month Plan
$179- $179 Billed Today
- Then $179 Every Month
- Cancel Anytime
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$179 billed today, then every month until canceled.
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Your provider confirms the strength and dose after intake. Payment does not guarantee a prescription.
After checkout you complete a short medical review in your member portal, and a US-licensed provider reviews it before your sermorelin ships.
Full refund if not prescribed Free, discreet shipping Cancel anytime
Order today and here is what happens next
- TodayChoose a plan, then a short online intake
- Within about 24 hoursA US-licensed provider reviews your request
- Ships in 3 to 5 daysEstimated ship date, if prescribed
- Full refund
- If a provider does not prescribe it
- Licensed clinicians
- An independent US-licensed clinician reviews every request
- US-licensed pharmacy
- Prepares and ships your prescription
- Discreet delivery
- Plain, unmarked packaging
Common questions
Is sermorelin the same as HGH?
No. Sermorelin is a growth hormone-releasing hormone analog that prompts your own pituitary to release growth hormone; HGH is the hormone itself, given directly. Sermorelin preserves your body's natural release pattern, while direct HGH bypasses that feedback loop entirely. We don't use the terms interchangeably, and neither should the marketing you see for either one.
Is sermorelin FDA-approved?
Not as it is sold today. Sermorelin acetate was the active ingredient of Geref, an FDA-approved product for testing and treating growth hormone deficiency in children, which is no longer marketed. FDA determined in 2013 that Geref was not withdrawn for reasons of safety or effectiveness. This plan is a compounded preparation, and adult use is off-label.
How much does sermorelin cost at HealthRX.com?
The plan selector on this page shows the current price of every plan before you pay, and longer plans cost less per month. Each plan includes the medication, an injection home kit, the online provider visit with follow-up messages, and shipping. You pay cash, and insurance is not needed. If the provider decides it is not right for you, you get a full refund.
LegitScript certifiedCert. 50087439- US-licensed pharmacyPrepares every prescription
- Independent cliniciansUS-licensed, in your state
- 40,000+Products sold
- All 50 statesFree, discreet shipping
- No insurance requiredOne price, shown up front
Winding down
Your pituitary, prompted, not replaced.
- 01Prompts your own GH
- 02Preserves pulsatile release
- 03At-home injection
- 04Provider-set dose
Illustrative photography with models, not patients.
Why Sermorelin
Preserves your natural GH pulses
It works with your pituitary's own pulsatile release pattern, rather than adding a constant supply from outside.
A simple at-home injection
A small subcutaneous injection you give yourself at night, with an injection kit included.
A provider sets your dose
A US-licensed provider reviews your history and goals first and sets your strength, with real pricing shown up front.
How we compare
Sermorelin, without the waiting room.
HealthRX.comTypical in-person visit
Start online, no appointment or waiting roomBook, travel and wait
A US-licensed clinician reviews your history
Price shown before you startDepends on the visit and insurance
No insurance requiredOften billed through insurance
Delivered to your door in a plain boxPick up at the pharmacy
Full refund if you are not prescribedVisit fees usually apply either way
Understand your treatment
Work through the body’s growth-hormone signal.
Sermorelin is a growth-hormone-releasing hormone analog. It acts on the pituitary signaling involved in growth-hormone release, rather than supplying growth hormone directly. This is the essential distinction when comparing peptide products: a signaling peptide and the hormone itself occupy different points in the pathway. Understanding the ingredient and its route helps keep the product discussion specific instead of grouping every peptide under the same recovery or vitality promise.
A closer look
Work through the body’s growth-hormone signal.
GHRH analog
Pituitary signaling
Growth-hormone release
Make a more informed choice
A releasing-hormone analog vs. growth hormone
Sermorelin acts upstream at the signaling stage. Growth hormone is the downstream hormone. The catalog’s injectable sermorelin option is a distinct formulation with its own plan.
Explore the ingredient research
- Growth-hormone-releasing factors in human subjects
- Review: sermorelin in children with growth hormone deficiency (Prakash and Goa, 1999)
- Nightly sermorelin (GHRH 1-29) injections in healthy older men (Vittone et al., 1997)
- Federal Register: Geref not withdrawn for reasons of safety or effectiveness (March 4, 2013)
A straightforward path to care
Select your plan
Choose your treatment options and complete secure checkout. Then complete the online health intake.
Provider review
A licensed physician (MD) reviews your completed intake and prescribes sermorelin only if it is appropriate for you.
Ships to your door
A US-licensed pharmacy compounds your dose and ships it free in discreet packaging, with an injection kit.
Ongoing support
Message your care team with questions, and your provider can adjust your dose over time.
- Provider review
- An independent US-licensed clinician reviews every request.
- Free, discreet shipping
- Filled by a US-licensed pharmacy and shipped in discreet packaging.
- Not prescribed?
- You get a full refund for the medication.
About Sermorelin
Sermorelin is a GHRH(1-29) analog, a lab-made copy of the first 29 amino acids of your body's own growth hormone-releasing hormone. Instead of putting growth hormone into your system directly, the way an rhGH injection does, it tells your pituitary gland to make and release its own, so your natural feedback loop and pulsatile release pattern stay intact. We want to be clear about the distinction, because marketing in this category often blurs it: sermorelin is not HGH, and your provider won't describe it as an equivalent.
- Stimulates your own pituitary rather than introducing exogenous growth hormone
- Acts on the GHRH pathway rather than supplying growth hormone directly
- Provider evaluation before prescribing
- Evidence disclosed honestly: mechanism is well established, long-term adult trial data is not
Sermorelin
binds GHRH receptors on your anterior pituitary
Pituitary gland
releases your own growth hormone in its natural pulses
Liver and tissues
respond to growth hormone as part of normal metabolism
Growth hormone is prompted from your own pituitary, not replaced from outside.
Sermorelin or Direct HGH
Two different approaches
| Sermorelin | Direct HGH | |
|---|---|---|
| How it works | Signals your pituitary to release your own growth hormone | Replaces growth hormone from an external source |
| Release pattern | Preserves your natural pulsatile release | Adds a continuous outside supply |
| Feedback control | Stays subject to your body's own feedback loops | Bypasses your body's feedback loops |
| Format | Small at-home subcutaneous injection | Growth hormone injection |
| Oversight | Provider-reviewed, prescribed off-label | Provider-reviewed, tightly restricted |
| Clinical context | Historical pediatric and diagnostic evidence; adult benefit claims need separate evidence | Diagnosed adult growth hormone deficiency |
What to expect
Sermorelin has historical FDA-approved uses in growth-hormone testing and pediatric growth-hormone deficiency. Those approvals do not establish adult benefits for energy, body composition, or aging. FDA determined in 2013 that the Geref products were not withdrawn for reasons of safety or effectiveness. That finding does not make this compounded preparation FDA approved or establish a predictable timeline for adult results.
Week 1 to 2
Start your injections
Begin your nightly subcutaneous dose after your provider confirms your prescription.
Week 3 to 6
Settle into the routine
Continue your regular dosing and message your care team anytime with questions.
Week 8 to 12
Check in with your provider
Your provider reviews how you are doing and can adjust your dose.
Ongoing
Provider tunes your plan
Your provider tailors your dose to your response and goals, with unlimited follow-ups.
Safety and side effects
This product is compounded by a licensed pharmacy and is not FDA-approved. It has not undergone FDA review for safety or efficacy; its adult use is off-label. Sermorelin is absolutely contraindicated in anyone with active or recent cancer, since stimulating growth hormone release carries theoretical risk in that setting. Reported reactions include nausea, dizziness, flushing, headache, a mild uptick in blood sugar, and irritation or redness at the injection site. Your provider will also weigh retinopathy, any pituitary tumor history, thyroid conditions, and diabetes before confirming a prescription, since each changes how closely you'll need to be monitored.
Common
- Redness or swelling at the injection site
- Flushing
- Headache
- Mild dizziness
Less common
- Nausea
- Drowsiness
- Joint aches or swelling
Seek care
- Allergic reaction such as rash, swelling, or trouble breathing
- It is not for anyone with an active cancer, since growth hormone can affect existing tumors
Sermorelin is compounded by a US-licensed pharmacy and prescribed off-label. It is not for anyone with active cancer or malignancy, and it is not for use during pregnancy or by anyone under 18. Tell your provider about every medication you take and any history of cancer before starting. This is not a complete list of side effects.
Frequently asked questions
What are the side effects of sermorelin?
In studies of sermorelin, the most commonly reported side effects were brief facial flushing and pain at the injection site (Prakash and Goa, 1999). A six-week study in 11 healthy men aged 64 to 76 reported no significant adverse effects (Vittone et al., 1997). Tell your provider about any history of cancer, and get emergency care for signs of an allergic reaction such as trouble breathing or swelling of the face.
What does sermorelin research in adults show?
Adult data are limited. In a six-week study, 11 healthy men aged 64 to 76 injected 2 mg of sermorelin under the skin each night. Night-time growth hormone release increased, but IGF-1, body composition, weight and lipids did not change, and two of six strength measures improved (Vittone et al., 1997). Adult studies have been small and short, so we do not promise changes in energy, body composition or ageing.
What sermorelin dose is used?
Published studies used once-nightly injections under the skin: 30 micrograms per kilogram of body weight in children with growth hormone deficiency (Prakash and Goa, 1999) and 2 mg in a study of older men (Vittone et al., 1997). Your provider sets your own dose and schedule, so follow your prescription rather than an online dosing chart.
Does sermorelin cause cancer?
There's no evidence that it causes cancer, but active or recent cancer is an absolute contraindication, since stimulating growth hormone release carries a theoretical risk in that setting. Your provider will ask directly about cancer history before confirming whether sermorelin is clinically appropriate for you.
How often is sermorelin injected?
Sermorelin is injected under the skin, usually once a day at bedtime in published studies, on a schedule your provider sets. Changes people look for, if they happen, build over weeks to months rather than after a single injection.
Who shouldn't take sermorelin?
Anyone with active or recent cancer, since that's an absolute contraindication. Your provider also proceeds with extra caution in people with diabetes, thyroid conditions, a history of pituitary tumor, or retinopathy. Because adult use is off-label and long-term trial data is still limited, your provider will walk through what the evidence does and doesn't show before prescribing.
Other longevity options
Everyday essentials for your routine.
No prescription needed. Dietary supplements for the daily habits around your care, sold separately from prescription treatment. Ask your provider before adding one to your routine.
Dietary supplements, not medications. These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Approval is never automatic.
An independent US-licensed clinician reviews every request. If they decide the treatment is not right for you, you get a full refund for the medication.
Choose a planNo insurance required
Prescriptions are filled by a US-licensed pharmacy and shipped free, in discreet packaging, on every plan.
LegitScript-certified · Cert 50087439
Compounded medications are prepared by a US-licensed pharmacy and are not reviewed by the FDA for safety or effectiveness. Products are dispensed only after a licensed provider determines they are appropriate. Information here is educational and is not a substitute for medical advice.