• LegitScript Certified
  • US-licensed 503A pharmacy
  • Free to join the list
Concentration
KPV acetate
Purity
Provider reviewed
Unit
By mouth or on the skin
Category
Longevity

Common questions

When will KPV be available?
As soon as our pharmacy adds it as a single-ingredient prescription. Join the list and we will text and email you the day it is ready. We do not have a date yet.
Why no KPV injection?
HHS's policy covers KPV taken by mouth or put on the skin, not injected. That is how ours will come.
Is KPV legal to prescribe now?
Yes, under conditions. In October 2026, HHS said it will not take enforcement action against state-licensed 503A pharmacies that compound KPV from a patient-specific prescription and meet the policy's conditions, while FDA finishes its rule. HHS covers it by mouth or on the skin. It is still not FDA approved.

KPV

KPV by prescription. Coming soon.

KPV is a three-amino-acid peptide, the tail end of the hormone alpha-MSH. HHS opened it to US 503A pharmacies in October 2026, by mouth or on the skin only. Our pharmacy is adding it as a single-ingredient prescription. Join the list to be first.

  • Coming soon
  • No injections
  • Provider reviewed
  • Free to join the list

Coming soon

Our pharmacy is adding KPV as a single-ingredient prescription. Join the list and be first to order.

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Understand your treatment

Three amino acids from a hormone you make.

KPV is the tail end of alpha-MSH, a hormone involved in skin color and inflammation signaling. Research has looked at it in the gut and skin. HHS covers KPV by mouth or on the skin only.

A closer look

Three amino acids from a hormone you make.

Lys-Pro-Val
PepT1
By mouth or on skin

Make a more informed choice

KPV vs. alpha-MSH

Alpha-MSH is a 13-amino-acid hormone. KPV is its last three amino acids. HHS's policy covers KPV acetate taken by mouth or applied to the skin, never injected.

Explore the ingredient research

A straightforward path to care

  1. Checkout on a laptop at a kitchen table

    Join the list

    Leave your email and mobile number. We tell you the day it is ready to order.

  2. Clinician reviewing a chart on a laptop

    Provider review

    The day our pharmacy can fill KPV as a single-ingredient prescription, you get a text and an email.

  3. Adult opening a delivered box at home

    Ships to your door

    Order online, do a short intake, and a US-licensed provider decides if KPV is right for you.

  4. Adult at home using a phone

    Ongoing support

    A state-licensed US 503A pharmacy makes it for you by name and ships it free in plain packaging.

Just three amino acids

Lys-Pro-Val, the last three amino acids of alpha-MSH, a hormone your body makes.

Studied in the gut

In mice, KPV in drinking water reduced colitis. In human gut cells it was taken up by the PepT1 transporter.

By mouth or on the skin

HHS's policy covers KPV taken by mouth or put on the skin, not injected. That is how ours will come.

First in line

Join the list and we will text and email you the day it is ready to order. Free, no payment now.

About KPV

KPV is the tripeptide Lys-Pro-Val, the last three amino acids of alpha-MSH, a hormone your body makes. Research has looked at it in the gut and skin. In gut cells it is taken up by PepT1, a peptide transporter. Ours will be KPV acetate as the only active ingredient, taken by mouth or put on the skin, compounded by a US 503A pharmacy.

  • Three amino acids: Lys-Pro-Val
  • KPV acetate, the only active ingredient
  • By mouth or on the skin, never injected
  • Prescribed after a US-licensed provider review

Sequence: Lys-Pro-Val (HHS Appendix B, 2026).

  1. Alpha-MSH

    a 13-amino-acid hormone your body makes

  2. Lys-Pro-Val

    its last three amino acids, KPV

  3. PepT1

    the gut transporter that took KPV into cells in a lab study

A three-amino-acid peptide, coming by mouth or on the skin.

Where KPV comes from

What the research shows

KPV research is mostly cell and mouse work. Here is what the record shows.

3

amino acids make up KPV: lysine, proline and valine.

HHS Appendix B, 2026

In mice

KPV given in drinking water reduced chemically induced colitis.

Dalmasso et al., Gastroenterology 2008

No needles

HHS's policy covers KPV by mouth or on the skin only.

HHS 503A peptide policy, 2026

HealthRX.com or Research-use sites

Two very different ways to get KPV

HealthRX.comResearch-use sites
Who makes itA state-licensed US 503A pharmacy, from your prescriptionOften overseas labs, sold as powder in a vial
Labeled forYou, by name, with your provider's directions"Research use only. Not for human use."
Who checks it fits youA US-licensed provider reviews your health historyNo one
What is in itKPV acetate, one ingredientThe seller's own claims
Questions laterMessage your care team anytimeSeller support, if any
PriceShown up front, full refund if not prescribedOften less per vial, with no medical review

What to expect

Here is what happens from joining the list to your first order.

  1. Today

    Join the list

    Free. No payment and no intake yet.

  2. Launch day

    You hear first

    We text and email you the moment it is ready to order.

  3. Then

    Order and do your intake

    Choose a plan, then a short online health intake for a provider to review.

  4. Within about a week

    It arrives

    If prescribed, the pharmacy ships it in plain packaging, with your directions on the label.

Safety and side effects

KPV is compounded by a US-licensed 503A pharmacy and is not FDA approved. FDA has not reviewed it for safety, effectiveness or quality, and human studies are small. A licensed provider reviews your health history and medicines before deciding whether to prescribe it. It is not for use during pregnancy or breastfeeding, or by anyone under 18. Report side effects to your provider, or to FDA MedWatch at 1-800-FDA-1088.

Common

  • Stomach upset
  • Skin irritation where a cream is applied

Less common

  • Irritation that does not settle after a few days

Seek care

  • Signs of an allergic reaction: hives, swelling of the face or throat, or trouble breathing

Human safety data for KPV are limited. Tell your provider about every medicine you take before starting. This is not a complete list of side effects.

Frequently asked questions

What does the research show?
In mice, KPV given in drinking water reduced colitis, and in human gut cells it was taken up by the PepT1 transporter (Dalmasso et al., 2008). Human studies are limited. Your provider will go through what is and is not known.
What will it cost?
We will show every price on this page before launch, with the online provider visit, the medication if prescribed and shipping included. Joining the list is free.
Who should not take KPV?
It is not for anyone pregnant, breastfeeding or under 18. Your provider reviews your health history and medicines before deciding.

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Approval is never automatic.

An independent US-licensed clinician reviews every request. If they decide the treatment is not right for you, you get a full refund for the medication.

Choose a planNo insurance required

Prescriptions are filled by a US-licensed pharmacy and shipped free, in discreet packaging, on every plan.

LegitScript-certified · Cert 50087439

Compounded medications are prepared by a US-licensed pharmacy and are not reviewed by the FDA for safety or effectiveness. Products are dispensed only after a licensed provider determines they are appropriate. Information here is educational and is not a substitute for medical advice.