Trulicity HSA/FSA Eligibility and Submission: A Complete 2026 Guide

Is Trulicity HSA- and FSA-Eligible?

Yes. Trulicity is a prescription medicine; the FDA approval record lists all four strengths as prescription-only [1]. Publication 502, the IRS publication on medical and dental expenses, lists drugs and medicines among the expenses it covers [2]. Publication 969 covers HSAs and health FSAs, including qualified medical expenses and recordkeeping for distributions [3].

Trulicity's label covers two uses: improving blood sugar control in adults and children 10 years of age and older with type 2 diabetes, and reducing the risk of cardiovascular death, non-fatal heart attack or non-fatal stroke in adults with type 2 diabetes who have established cardiovascular disease or multiple cardiovascular risk factors [4]. The label has no weight-loss or chronic weight management indication [4].

What the IRS Publications Cover

Publication 502 organizes medical expenses by category, including drugs, medicines, laboratory fees, hospital services and insurance premiums, rather than by brand name [2]. A Trulicity purchase falls under the drug or medicine categories.

An eligible Trulicity prescription can be paid for with available HSA or health FSA funds, or submitted for reimbursement under the account's rules [2][3].

HSA and FSA: Different Accounts, Same Expense Test

Publication 969 covers HSAs and health FSAs in separate sections, and both sections address qualified medical expenses [3]. It also covers HSA eligibility topics that include other health coverage, prescription drug plans, enrolling in Medicare, and the health FSA grace period [3].

Records for a Trulicity Claim

Recordkeeping is one of the topics Publication 969 covers for HSA distributions [3]. Records for a Trulicity expense follow the rules of the HSA or health FSA that pays for it [3]. The expense itself is a drug or medicine under Publication 502 [2].

Does Medicare Enrollment Matter?

Publication 969 addresses HSA rules for people enrolled in Medicare as part of its HSA contribution material, and covers qualified medical expenses for distributions in a separate section [3].