Guidelines for Prediabetes Management and Diagnosis
ADA criteria: fasting glucose 100-125 mg/dL, A1c 5.7-6.4%, or OGTT 140-199 mg/dL. Screening starts at age 35. See the full diagnostic algorithm.
Prediabetes (Condition)
12 source-based articles maintained by the HealthRX.com Editorial Team.
12articles
4topic areas covered
May 26, 2026latest review
Prediabetes (Condition) library
Showing 12 of 12 clinical reviews.
Management of Prediabetes Guidelines: Treatment Algorithm
Prediabetes management starts with lifestyle changes targeting 7% weight loss, then metformin for high-risk patients, then GLP-1 agonists if obesity persists.
Prediabetes and Mental Health: The Bidirectional Link Explained
Prediabetes and mental health disorders share overlapping biology, risk factors, and treatment gaps. Learn how depression, anxiety, and chronic stress drive glucose dysregulation, and what clinical guidelines say about screening and treating both.
Prediabetes Annual Evaluation Checklist: What to Test, When, and Why
A complete prediabetes annual evaluation checklist covering A1c, fasting glucose, lipids, blood pressure, kidney function, and lifestyle targets, with ADA and USPSTF guideline citations and clinical trial data.
Prediabetes Caregiver and Family Resources
Evidence-based guide for caregivers and families supporting someone with prediabetes, including lifestyle strategies, screening recommendations, shared-risk awareness, and practical tools from the ADA, CDC, and major clinical trials.
Prediabetes Emerging Research and Trials to Watch
A guide to the most promising prediabetes research, from GLP-1 receptor agonists and dual-incretin therapies to precision diagnostics and microbiome interventions. Includes key trials, timelines, and clinical implications.
Prediabetes Exercise Prescription: Evidence-Based Protocols That Lower Your Risk
A guide to exercise protocols for prediabetes, including specific intensity targets, resistance training recommendations, and the trial data behind each prescription.
Prediabetes Guidelines Compared: ADA, AACE, Endocrine Society, and USPSTF
A head-to-head comparison of prediabetes diagnostic thresholds, treatment targets, and pharmacotherapy recommendations from ADA, AACE, the Endocrine Society, and USPSTF, with primary-source citations and clinical decision guidance.
Prediabetes History of Treatment Over Decades
A clinical deep-dive into how prediabetes treatment has evolved from lifestyle-only advice in the 1980s through modern pharmacotherapy and precision medicine, with primary-source citations and actionable guidance.
Prediabetes Nutrition and Lifestyle Protocols: Evidence-Based Strategies to Prevent Type 2 Diabetes
Complete guide to prediabetes nutrition protocols, lifestyle interventions, and pharmacotherapy options backed by the Diabetes Prevention Program and ADA guidelines.
Prediabetes Open Controversies in the Field
A clinically rigorous review of the most contested debates in prediabetes research: diagnostic thresholds, reversal definitions, treatment with metformin, overdiagnosis risk, and what current guidelines actually recommend.
Prediabetes Racial and Ethnic Disparities: Prevalence, Risk, and What to Do About It
Why prediabetes rates differ sharply by race and ethnicity, which populations carry the highest burden, and what ADA and USPSTF guidelines recommend for equitable screening and treatment.