Public record

Insulin degludec: the public record

5 tables from US federal sources. Latest data date: Nov 11, 2026.

Each table is computed from the named federal dataset as of its data date; the method is under each one.

Label

FDA label facts for insulin degludec

The FDA label read for insulin degludec (Tresiba, application BLA203314) was last revised on 2022-07-01. It carries no boxed warning. Of the 4 population sections checked, 4 are present: pregnancy, lactation, pediatric use, geriatric use.

FDA label facts for insulin degludec: the figures
MeasureValueNote
Label revision date2022-07-01
Label readTresibaBLA203314, brand-name application
Boxed warningNo
Indications section opensquoted in note"TRESIBA is indicated to improve glycemic control in patients 1 year of age and older with diabetes mellitus."
Pregnancy sectionPresent
Lactation sectionPresent
Pediatric use sectionPresent
Geriatric use sectionPresent

Source: FDA drug label via openFDA, viewable on NIH DailyMed, data as of Nov 11, 2026

How this was calculated

Selected the most recently revised prescription label for this single ingredient from an original manufacturer, preferring a brand-name application. Checked which sections exist and quoted headings and sentences exactly as printed.

Scope: One label: the newest prescription label for single-ingredient insulin degludec from an original manufacturer

Read from one label. Labels for other brands, strengths or forms of the same ingredient can differ. A missing section heading does not mean there is no guidance. Read the full label before relying on it.

Download the data (CSV)

Medicare Part D

Medicare Part D spending on insulin degludec

Medicare Part D spending on insulin degludec products was $1.85B in 2024 across 2,321,262 claims, compared with $1.81B in 2023 (+2.3%). Average spending per claim was $798, before rebates.

Medicare Part D spending on insulin degludec: the figures
MeasureValueNote
Total spending, 2024$1.85B
Total spending, 2023$1.81B
Change in spending, 2023 to 2024+2.3%
Claims (prescription fills), 20242,321,262
Average spending per claim, 2024$798
Tresiba Flextouch U-200: spending, 2024$973.9M893,822 claims
Tresiba Flextouch U-100: spending, 2024$825.8M1,281,963 claims
Tresiba: spending, 2024$33.5M51,551 claims

Source: CMS, Medicare Part D Spending by Drug, data as of 2024

How this was calculated

Summed total spending and claims over every brand and generic row with this generic name in the CMS file, using the Overall manufacturer rows. Combination products excluded. Average per claim is spending divided by claims.

Scope: Every single-ingredient insulin degludec product in Part D (Tresiba Flextouch U-200, Tresiba Flextouch U-100, Tresiba), 2024.

Gross drug cost before manufacturer rebates, so net cost is lower. Part D excludes some uses by law (for example erectile dysfunction, weight loss and hair growth), so claims reflect covered uses only. Compounded products are not included.

Download the data (CSV)

Medicaid

Medicaid prescriptions for insulin degludec by state

State Medicaid programmes paid for 249,204 insulin degludec prescriptions in 2025, with $143.8M reimbursed before rebates. California reported the most (42,586), followed by Texas (17,629) and New York (14,711); 51 states and territories reported any.

Medicaid prescriptions for insulin degludec by state: the figures
MeasureValueNote
Prescriptions paid by Medicaid, 2025249,204
Total reimbursed before rebates, 2025$143.8M
States and territories reporting51with at least one count CMS did not suppress
California42,586 prescriptions$28.1M reimbursed
Texas17,629 prescriptions$8.4M reimbursed
New York14,711 prescriptions$8.6M reimbursed
Connecticut14,495 prescriptions$10.0M reimbursed
Indiana13,652 prescriptions$9.2M reimbursed

Source: CMS, Medicaid State Drug Utilization Data 2025, data as of 2025

How this was calculated

Matched each Medicaid product code to the FDA NDC Directory by labeler and product code, kept finished single-ingredient products, then summed prescriptions and reimbursement by state. National roll-up and suppressed rows dropped.

Scope: All single-ingredient insulin degludec products in the FDA NDC Directory, fee-for-service and managed care, 2025

Counts under 11 are suppressed by CMS and left out, so totals are a floor. Amounts are before rebates. Differences between states reflect programme size and coverage rules. Compounded products are not included.

Download the data (CSV)

Pharmacy cost

Pharmacy acquisition cost (NADAC) for insulin degludec

Retail pharmacies paid an average of $11.34 per mL for INSULIN DEGLUDEC 100 UNIT/ML VIAL as of 2026-11-11, compared with $11.37 twelve months earlier (-0.3%). This is a pharmacy purchase cost, not a patient price.

Pharmacy acquisition cost (NADAC) for insulin degludec: the figures
MeasureValueNote
INSULIN DEGLUDEC 100 UNIT/ML VIAL$11.34 per mL12 months earlier $11.37 (-0.3%)
INSULIN DEGLUDEC FLEXTOUCH 100 UNIT/ML PEN$11.39 per mL12 months earlier $11.38 (+0.1%)
INSULIN DEGLUDEC FLEXTOUCH 200 UNIT/ML PEN$22.74 per mL12 months earlier $22.73 (+0.0%)

Source: CMS, National Average Drug Acquisition Cost (NADAC), data as of Nov 11, 2026

How this was calculated

Matched NADAC product codes to the FDA NDC Directory, kept finished single-ingredient products, and listed the product descriptions with the most package codes. The earlier price is the same package code in the file one year before.

Scope: Generic versions of insulin degludec in the weekly NADAC file of 2026-11-11, compared with the file of 2025-11-12

NADAC is the average invoice price retail pharmacies pay, from a voluntary survey. It leaves out rebates, dispensing fees and markups, and it is not what a patient or insurer pays. Compounded products are not surveyed.

Download the data (CSV)

Clinical studies

Registered clinical studies of insulin degludec

ClinicalTrials.gov lists 251 registered studies that name insulin degludec as an intervention as of 2026-11-11. Of these, 8 are recruiting, 207 are completed and 87 are phase 3 studies.

Registered clinical studies of insulin degludec: the figures
MeasureValue
Registered studies251
Recruiting now8
Not yet recruiting4
Completed207
Terminated, withdrawn or suspended7
Phase 3 (including phase 2/3)87
Phase 2 (including phase 1/2)19
Phase 165

Source: NIH National Library of Medicine, ClinicalTrials.gov, data as of Nov 11, 2026

How this was calculated

Searched the ClinicalTrials.gov intervention field for the name, downloaded every matching record and counted by overall status and phase. Combined phases are counted under the higher phase. Phase not applicable covers observational, device and behavioural studies.

Scope: Studies whose intervention field matches insulin degludec, any condition, any country, all statuses

A registered study is not a result. Counts include studies where the drug is a comparator or background treatment, and studies that never finished or reported.

Download the data (CSV)

Articles on Insulin degludec