DHEA Drug Interactions: Which Meds Raise or Lower DHEA-S
Glucocorticoids, metformin, and carbamazepine suppress DHEA-S, while DHEA supplements and valproate raise it. See which drugs skew your result.
14 source-based articles maintained by the HealthRX.com Editorial Team.

Showing 14 of 14 clinical reviews.
Glucocorticoids, metformin, and carbamazepine suppress DHEA-S, while DHEA supplements and valproate raise it. See which drugs skew your result.
Complete guide to DHEA-S testing at home or via finger-prick, including normal ranges by age and sex, optimal longevity targets, and how to interpret your result with a telehealth provider.
A guide to DHEA-S normal ranges, optimal targets, and age-specific interpretation from your 20s through your 70s and beyond, with primary-literature citations.
Understand why standard DHEA-S reference ranges may not reflect your best health. Learn the difference between lab-normal and clinically optimal DHEA-S, plus how to raise or lower levels safely.
A guide to DHEA-S reference ranges, longevity-medicine targets, age-related decline, and when supplementation with DHEA is supported by evidence. Includes specific trial data, dosing guidance, and monitoring protocols.
A clinical guide to how medications, hormones, and supplements shift DHEA-S levels, what the optimal range looks like by age and sex, and how to interpret results in the context of HRT, corticosteroids, and GLP-1 therapy.
How diet, caloric restriction, fasting, and specific nutrients shift DHEA-S levels, what the optimal range looks like, and when to retest after a dietary change.
Learn how to interpret DHEA-S rate-of-change across serial labs, understand age-adjusted normal ranges, and know when a declining or rising trend requires clinical action.
A clinical guide to DHEA-S reference ranges by sex, age, and menstrual cycle phase, what 'optimal' means beyond the lab's normal range, and when an abnormal result needs further workup.
How resistance training, aerobic exercise, overtraining, and periodization affect DHEA-S levels, what the optimal range looks like, and how HealthRX.com clinicians interpret results in active patients.
Learn how to raise or lower DHEA-S levels using clinically validated strategies, including supplementation, lifestyle changes, and medications backed by peer-reviewed research.
Learn what your DHEA-S blood test result means, including normal ranges by age and sex, what high or low levels indicate, and when to act on abnormal findings.
Learn when clinicians order a DHEA-S blood test, what normal ranges look like by age and sex, and how to interpret high or low results in the context of adrenal and hormonal health.
A clinician-guided breakdown of the lab tests to pair with DHEA-S, including cortisol, testosterone, SHBG, 17-hydroxyprogesterone, and more, with reference ranges and interpretation tips.

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