Pioglitazone: Regulatory History

2 source-based articles maintained by the HealthRX.com Editorial Team.

2articles

1topic areas covered

May 26, 2026latest review

Pioglitazone: Regulatory History library

Showing 2 of 2 clinical reviews.

SafetyMay 26, 2026

Actos (Pioglitazone) FDA Approval History: Timeline, Label Changes, and Safety Updates

Complete FDA approval history of pioglitazone (Actos), including original 1999 approval, black box warnings, bladder cancer reviews, and current prescribing label status.

SafetyMay 27, 2026

Actos (Pioglitazone) Label Updates 2020 to 2026: FDA Safety Changes, Warnings, and Clinical Context

A review of pioglitazone (Actos) label content and FDA safety communications relevant to prescribing decisions from 2020 through 2026, covering bladder cancer language, heart failure warnings, bone fracture risk, and off-label NASH/MASH use, with explicit flags where source figures require independent verification.