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63 clinically reviewed articles, written and peer-reviewed by the HealthRX.com Medical Team.
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Showing 63 of 63 clinical reviews.
GLP-1 receptor agonists have been in clinical use since 2005. This evidence-based review covers the full safety record, major trials, FDA warnings, and what patients starting these medications should know.
Read clinical reviewA clinician-reviewed guide explaining exactly which hormones drive weight gain, the mechanisms behind each, and what evidence-based treatments can help you lose the weight and keep it off.
Read clinical reviewA clinician-reviewed guide explaining which pre-existing conditions qualify or disqualify you from Calibrate's GLP-1 weight-loss program, with evidence-based context on semaglutide, liraglutide, and metabolic health.
Read clinical reviewLevothyroxine can cause anxiety, particularly when the dose is too high. Learn how overdose symptoms differ from undertreated hypothyroidism, what the evidence shows, and how to adjust your treatment.
Read clinical reviewMounjaro (tirzepatide) is not approved for general weight loss in all adults. Learn who qualifies, who should avoid it, what the clinical data show, and how to find out if you are a candidate.
Read clinical reviewA complete clinical guide to conception with hormonal imbalance: which hormones matter, how they disrupt ovulation, and what treatments actually work to restore fertility.
Read clinical reviewYes, PCOS and endometriosis can co-exist. Learn how these two conditions overlap, why dual diagnosis is often missed, and what treatment looks like when you have both.
Read clinical reviewLearn which blood tests, symptoms, and clinical criteria doctors use to diagnose perimenopause, what FSH, estradiol, and AMH levels mean, and when hormone testing actually helps.
Read clinical reviewGLP-1 receptor agonists slow gastric emptying, which can reduce or delay the absorption of oral medications taken at the same time. Learn which drugs are most affected, what the clinical data show, and how to time your medications safely.
Read clinical reviewA clinician-reviewed breakdown of the current evidence on hormone replacement therapy and dementia risk, including the 2023 BMJ mega-cohort, the Women's Health Initiative Memory Study, and what the data actually mean for women considering HRT.
Read clinical reviewLevothyroxine restores thyroid hormone levels in hypothyroidism, which can reverse the weight gain caused by a slow metabolism. But for people with normal thyroid function, it does not produce meaningful fat loss and carries real risks. Read the full clinical picture.
Read clinical reviewYes, menopause can cause hair loss. Falling estrogen and progesterone levels shift hair follicles into a resting phase while rising androgen activity shrinks them. Learn the mechanisms, treatment options, and what the evidence actually shows.
Read clinical reviewYes, menopause causes fatigue through falling estrogen, disrupted sleep, and thyroid overlap. This evidence-based guide covers why it happens, how to confirm the cause, and what actually works to restore energy.
Read clinical reviewA clinician-reviewed guide to how thyroid, cortisol, insulin, estrogen, testosterone, melatonin, and GLP-1 hormones interact to drive or stall weight loss, disrupt sleep, and drain energy, with specific doses, trials, and actionable clinical steps.
Read clinical reviewExplore the evidence-based fitness, nutrition, hormone, and recovery strategies that help women over 40 maintain muscle, energy, and metabolic health, grounded in clinical research and real physiology.
Read clinical reviewA physician-reviewed guide covering thyroid, insulin, progesterone, estrogen, and androgens, with specific labs, doses, and timelines to optimize your hormonal environment before conception.
Read clinical reviewA science-backed guide for women over 35 and moms looking to build lean muscle, reduce body fat, and support hormonal health through evidence-based training, nutrition, and recovery strategies.
Read clinical reviewMenopause hair loss affects up to 50% of women over 50. Learn what causes it, which treatments have clinical evidence behind them, and what your doctor can actually prescribe.
Read clinical reviewEvidence-based strategies for correcting hormonal imbalances that cause fatigue, irritability, and low mood, including thyroid optimization, sex hormone therapy, cortisol management, and lifestyle interventions.
Read clinical reviewFive clinician-backed strategies to restore hormonal balance, covering sleep, nutrition, exercise, stress, and medical evaluation with specific protocols and trial data.
Read clinical reviewLearn the clinical signs, lab markers, and evidence-based strategies to identify a slowing metabolism, including thyroid function, hormonal changes, and actionable next steps.
Read clinical reviewLearn the early warning signs of low blood sugar (hypoglycemia), what causes dangerous drops, and evidence-based solutions to treat and prevent episodes safely.
Read clinical reviewBody-type dieting lacks clinical evidence. Learn what actually predicts dietary success, including thyroid function, insulin sensitivity, and metabolic markers, plus how to match your eating pattern to your biology.
Read clinical reviewAfter 40, hormonal shifts, muscle loss, and metabolic slowdown make standard calorie-cutting ineffective. Learn what the clinical evidence actually supports for sustainable fat loss at this life stage.
Read clinical reviewA clinician-reviewed guide to the sleep-hormone connection, covering cortisol, melatonin, growth hormone, insulin, thyroid, sex hormones, and evidence-based strategies to improve both sleep quality and hormonal health.
Read clinical reviewA clinical guide to the six evidence-based steps that optimize fertility, reduce pregnancy complications, and protect fetal development from day one, written by the HealthRX medical team.
Read clinical reviewLearn how to interpret TSH, free T4, free T3, testosterone, estradiol, and other hormone lab values. Understand reference ranges, optimal zones, and when results signal a need for treatment.
Read clinical reviewA clinician-reviewed guide to reversing menopausal hair thinning: causes, proven treatments, dosing, and when to see a specialist.
Read clinical reviewLearn exactly which blood tests, antibody panels, and imaging studies diagnose Hashimoto's thyroiditis, what the results mean, and when to see a specialist.
Read clinical reviewA physician-reviewed guide explaining every thyroid lab test used to diagnose hypothyroidism, including TSH, Free T4, Free T3, antibody panels, and what your results actually mean.
Read clinical reviewA complete clinical guide to at-home hormone testing: which tests are accurate, what each biomarker means, how to collect samples correctly, and when to follow up with a physician.
Read clinical reviewA comprehensive, physician-reviewed guide covering GLP-1 safety in women, semaglutide side effects by system, pregnancy considerations, hormonal interactions, and what the clinical evidence actually shows.
Read clinical reviewHigh-volume cardio and low testosterone often show up together, but correlation is not causation. Learn what the research says about endurance training, T levels, and when exercise crosses from healthy to hormonally costly.
Read clinical reviewHow gut dysbiosis disrupts estrogen metabolism, thyroid conversion, and insulin signaling to stall fat loss in women, plus evidence-based strategies to restore the gut-hormone axis.
Read clinical reviewEvidence-based guide on when and how to take levothyroxine for maximum absorption, including timing, food interactions, drug interactions, and clinical dosing protocols reviewed by the HealthRX medical team.
Read clinical reviewA clinician-reviewed guide to every major safety warning for Zepbound (tirzepatide), including the boxed warning for thyroid C-cell tumors, pancreatitis risk, gallbladder events, and renal injury.
Read clinical reviewLearn what an endocrinologist does, which conditions they treat, how they differ from other doctors, and when you should ask for a referral. Written by the HealthRX.com medical team and reviewed by board-certified physicians.
Read clinical reviewZepbound (tirzepatide) is a dual GIP/GLP-1 receptor agonist approved for chronic weight management. Learn about dosing, clinical trial results, side effects, cost, and how it compares to semaglutide.
Read clinical reviewA clinician-reviewed guide explaining how specific nutrients, hormonal shifts, and dietary patterns affect hair loss and hair growth during menopause, with evidence-based strategies to support scalp and follicle health.
Read clinical reviewA clinician-reviewed guide covering peptide therapy safety, regulation, efficacy data, and what questions every woman should ask before starting a peptide protocol.
Read clinical reviewStandard lab panels miss ferritin patterns, diurnal cortisol rhythms, advanced lipid fractions, and functional thyroid markers. Learn which additional tests clinicians order when patients feel sick despite 'normal' results.
Read clinical reviewDeclining estrogen, progesterone, and thyroid shifts after 35 change gut motility, microbiome composition, and bile acid metabolism. Learn why bloating and digestive problems spike in perimenopause and what to do about it.
Read clinical reviewA complete guide to the lab tests required before your first Calibrate clinical visit, including TSH, fasting glucose, lipids, and more, with clinical context for each marker.
Read clinical reviewA complete guide to the pre-visit lab panel required before your Calibrate clinician appointment, including which biomarkers matter, why each is ordered, and how to prepare for accurate results.
Read clinical reviewA complete guide to the blood tests and lab panels your doctor may order before a metabolic health, weight management, or hormone therapy appointment, including thyroid, lipid, glucose, and hormone panels.
Read clinical reviewA complete guide to the lab tests required before your first Calibrate appointment: what each test measures, why it matters for GLP-1 and metabolic therapy, and how to get your results fast.
Read clinical reviewA clinically detailed guide to who qualifies for metabolic health programs like Calibrate, including BMI thresholds, comorbidity criteria, contraindications, and what to expect from GLP-1-based telehealth care.
Read clinical reviewA physician-reviewed guide to Wegovy® (semaglutide 2.4 mg) eligibility: BMI cutoffs, weight-related conditions, contraindications, lab workup, and how telehealth programs like Calibrate fit in.
Read clinical reviewFind out exactly who qualifies for Calibrate's GLP-1 metabolic health program, including BMI cutoffs, medical exclusions, insurance requirements, and how eligibility compares to FDA labeling for semaglutide and tirzepatide.
Read clinical reviewA detailed clinical breakdown of who cannot safely use Ozempic® (semaglutide), covering absolute contraindications, relative contraindications, off-label use limits, and what your prescriber checks before writing the script.
Read clinical reviewA physician-reviewed guide to absolute contraindications, relative cautions, and high-risk populations for GLP-1 receptor agonist therapy, including semaglutide and tirzepatide.
Read clinical reviewLab results expire, hormones fluctuate, and new providers need current baselines. Learn exactly why repeat bloodwork is medically necessary for safe thyroid and metabolic care.
Read clinical reviewThyroid symptoms can wax and wane due to autoimmune activity, medication timing, stress, sleep, and more. A board-reviewed guide explaining every major cause of fluctuating thyroid symptoms, with citations and a clinical action plan.
Read clinical reviewHormonal shifts, muscle loss, thyroid changes, and metabolic adaptation make cookie-cutter diets fail after 35. Learn the science and what actually works.
Read clinical reviewGetting a menopause diagnosis can take years. Learn why symptoms are dismissed, what tests actually matter, and how to advocate for proper care with evidence-based guidance from the HealthRX medical team.
Read clinical reviewStrength training protects cognitive function during menopause by raising BDNF, preserving hippocampal volume, and offsetting estrogen-related neurological decline. Here is what the clinical evidence says.
Read clinical reviewNaomi Watts trains consistently through menopause. Here is the neuroscience behind why exercise protects the menopausal brain, what the clinical data says, and what your training plan should actually look like.
Read clinical reviewChronic stress disrupts cortisol, thyroid, sex hormones, and insulin even in people with no diagnosed condition. Learn the mechanisms, the lab markers to request, and what to do about it.
Read clinical reviewA clinically grounded breakdown of why the 3-day diet and calorie cycling produce weight loss, what the research actually shows, and how to apply it safely.
Read clinical reviewFatigue and weight gain after 35 are rarely about willpower. This clinically reviewed guide explains the hormonal, metabolic, and thyroid-related reasons, with real data, dosing context, and actionable next steps.
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