Topic Hub
59 clinically reviewed articles, written and peer-reviewed by the HealthRX Medical Team.
Explore
Showing 59 of 59 clinical reviews.
A clinician-reviewed guide to acne vulgaris, male and female pattern hair loss, telogen effluvium, and alopecia areata. Covers FDA-approved drugs, dosing, trial data, and when to seek care.
Read clinical reviewEvidence-based guide to adapalene (Differin) covering mechanism, dosing, side effects, comparison with tretinoin, tazarotene, trifarotene, and topical minoxidil for acne, photoaging, and hair loss.
Read clinical reviewA clinician-reviewed guide to adolescent acne covering pathophysiology, evidence-based treatments (topical and systemic), hormonal therapies, hair loss in teens, pregnancy-safe options, and postmenopausal skin changes.
Read clinical reviewA clinical guide to alopecia areata covering autoimmune causes, JAK inhibitor therapies (baricitinib, ritlecitinib), corticosteroid injections, differential diagnosis from other hair loss types, and long-term management.
Read clinical reviewA clinician-reviewed guide to atopic dermatitis diagnosis, current systemic and biologic therapies, and the skin-hair overlap conditions including alopecia areata, telogen effluvium, and androgenetic alopecia.
Read clinical reviewA clinician-reviewed guide to azelaic acid for acne, rosacea, and hyperpigmentation. Covers FDA-approved formulations, combination therapy with tretinoin and adapalene, side effects, and who qualifies for prescription strength.
Read clinical reviewEvidence-based guide to bimatoprost (Latisse), tretinoin (Retin-A), tazarotene (Tazorac), adapalene (Differin), and trifarotene (Aklief), doses, mechanisms, clinical trial data, and how to choose.
Read clinical reviewWhat does compounded topical finasteride actually cost? We break down pharmacy pricing, insurance coverage, compounding fees, and how it compares to oral finasteride and other hair loss treatments.
Read clinical reviewOral minoxidil for hair loss costs $10, $90/month depending on pharmacy, dose, and insurance. Compare generic, compounded, and brand pricing with savings strategies.
Read clinical reviewA clinician-reviewed guide to crisaborole (Eucrisa) for eczema, including trial data, dosing, side effects, cost, and comparisons with topical retinoids like tretinoin, adapalene, tazarotene, and trifarotene.
Read clinical reviewA physician-reviewed guide to cystic acne covering isotretinoin, hormonal therapy, antibiotics, and emerging treatments with clinical trial data and dosing protocols.
Read clinical reviewAn evidence-based look at post-finasteride syndrome: what the clinical data shows, the nocebo debate, FDA warnings, risk factors, and what men considering finasteride for hair loss need to know.
Read clinical reviewMinoxidil is the only FDA-approved topical treatment for female pattern hair loss. Learn how it works, expected timelines, oral vs. topical options, side effects, and what clinical trials show about efficacy in women.
Read clinical reviewA clinician-reviewed guide to dupilumab (Dupixent), the IL-4/IL-13 inhibitor approved for atopic dermatitis, asthma, CRSwNP, eosinophilic esophagitis, and prurigo nodularis. Includes trial data, dosing, side effects, and how it fits alongside topical retinoids.
Read clinical reviewDupixent (dupilumab) causes conjunctivitis in up to 28% of atopic dermatitis patients. Learn the mechanism, risk factors, symptoms, and evidence-based management strategies.
Read clinical reviewDutasteride (Avodart) inhibits both type 1 and type 2 5-alpha reductase, reducing scalp DHT by roughly 90%. This guide covers off-label use for androgenetic alopecia, head-to-head data versus finasteride, dosing, side effects, and what to expect.
Read clinical reviewFemale pattern hair loss (FPHL) affects up to 50% of women by age 50. Learn about causes, diagnostic workup, FDA-approved treatments like minoxidil, and emerging therapies backed by clinical evidence.
Read clinical reviewA matched cross-trial synthesis of four major RCTs comparing finasteride and dutasteride for androgenetic alopecia, covering hair count changes, global assessments, patient satisfaction, and sexual side effect profiles.
Read clinical reviewA clinician-reviewed guide covering hirsutism, male pattern hair loss, female pattern hair loss, telogen effluvium, and alopecia areata. Includes FDA-approved treatments, diagnostic criteria, and dosing details.
Read clinical reviewA clinician-reviewed guide to realistic treatment timelines for isotretinoin (Accutane), minoxidil, finasteride, and tretinoin, with specific trial data, dosing benchmarks, and safety facts.
Read clinical reviewA clinician-reviewed guide to hydroquinone cream and gel, covering how it works, OTC vs. prescription strengths, combination therapy with retinoids like tretinoin and adapalene, safety data, and who should avoid it.
Read clinical reviewEvidence-based guide to hyperpigmentation types, proven treatments including hydroquinone, tretinoin, and chemical peels, plus prevention strategies from board-certified dermatology sources.
Read clinical reviewMicroneedling for hair loss shows strong clinical evidence when combined with minoxidil or finasteride. Review of trials, needle depths, protocols, and expected regrowth timelines.
Read clinical reviewA physician-reviewed guide to the long-term safety of oral minoxidil for hair loss, covering cardiovascular effects, fluid retention, hypertrichosis, real trial data, and how it compares to topical minoxidil.
Read clinical reviewA clinician-reviewed guide to isotretinoin (Accutane), tretinoin (Retin-A), adapalene (Differin), tazarotene (Tazorac), and trifarotene (Aklief), covering efficacy, dosing, side effects, and how to choose the right retinoid.
Read clinical reviewHow to calculate your isotretinoin cumulative dose by weight, what low-dose oral minoxidil looks like in practice, and how compounded topical finasteride compares to oral. Written by the HealthRX medical team.
Read clinical reviewA clinical comparison of isotretinoin and spironolactone for acne, plus finasteride vs dutasteride, topical vs oral minoxidil, tretinoin vs retinol, and PRP vs minoxidil for hair loss. Evidence-based guidance from the HealthRX medical team.
Read clinical reviewA complete clinical guide to isotretinoin's teratogenic risks, the iPLEDGE REMS program requirements, monthly pregnancy testing, contraception mandates, and what happens if a pregnancy occurs during treatment.
Read clinical reviewA clinician-reviewed guide to androgenetic alopecia in men covering DHT biology, Norwood staging, FDA-approved drugs (finasteride, minoxidil, dutasteride), emerging therapies, and when to consider hair transplantation.
Read clinical reviewEvidence-based guide to melasma causes, first-line treatments like triple combination cream and tranexamic acid, sunscreen protocols, and when to see a dermatologist.
Read clinical reviewEvidence-based guide to male pattern hair loss covering FDA-approved treatments like finasteride and minoxidil, emerging therapies, and when to see a specialist.
Read clinical reviewOral finasteride (Propecia) is an FDA-approved 5-alpha reductase inhibitor for male pattern hair loss. Learn about dosing, clinical trial results, side effects, and how it compares to topical alternatives.
Read clinical reviewA physician-reviewed guide to low-dose oral minoxidil for androgenetic alopecia and other hair loss types, covering doses, efficacy data, side effects, and how it compares to topical minoxidil.
Read clinical reviewA physician-reviewed guide to the oral minoxidil low dose protocol for hair loss, covering 0.25 to 5 mg dosing tiers, evidence from randomized trials, compounded topical finasteride, and isotretinoin weight-based dosing.
Read clinical reviewLow-dose oral minoxidil (1.25-5 mg) has quietly displaced topical minoxidil in dermatology practice. The HealthRX Medical Team argues the evidence base and safety profile at these doses justify making oral the first-line choice for most adults with androgenetic alopecia.
Read clinical reviewLearn how estrogen decline after menopause drives skin thinning, hair loss, and acne, plus evidence-based treatments including HRT, minoxidil, finasteride, and topical retinoids, reviewed by the HealthRX medical team.
Read clinical reviewA physician-reviewed guide to managing acne during pregnancy, covering safe topical and oral treatments, ingredients to avoid, and evidence-based protocols for every trimester.
Read clinical reviewA clinician-reviewed comparison of PRP therapy vs minoxidil for hair loss, plus finasteride vs dutasteride, topical vs oral minoxidil, and tretinoin vs retinol. Includes trial data, dosing, and a decision framework.
Read clinical reviewA clinician-reviewed guide to psoriasis covering pathophysiology, FDA-approved systemic and biologic therapies, and how psoriasis overlaps with scalp hair loss conditions including telogen effluvium and alopecia areata.
Read clinical reviewA clinician-reviewed guide to prescription and evidence-based treatments for skin aging, hair loss, and medical aesthetics, including tretinoin, minoxidil, GHK-Cu peptides, PRP, and GLP-1 effects on skin quality.
Read clinical reviewSpironolactone treats hormonal hair loss and acne in women by blocking androgens. Learn how it works, what the evidence shows, and how topical retinoids like tretinoin, adapalene, tazarotene, and trifarotene complement skin goals.
Read clinical reviewA clinician-reviewed guide to tazarotene (Tazorac) covering acne, photoaging, and psoriasis indications, head-to-head comparisons with tretinoin, adapalene, and trifarotene, dosing protocols, and side-effect management.
Read clinical reviewTelogen effluvium causes diffuse hair shedding 2-3 months after a trigger. Learn how TE differs from pattern hair loss and alopecia areata, what treatments work, and when hair regrows.
Read clinical reviewA clinician-reviewed guide to topical clindamycin for acne, including combination therapy with tretinoin, adapalene, tazarotene, and trifarotene, plus resistance data and prescribing details.
Read clinical reviewA clinician-reviewed guide to topical dapsone gel for acne, including clinical trial data, dosing, side effects, and head-to-head comparisons with tretinoin, adapalene, tazarotene, and trifarotene.
Read clinical reviewA clinical guide to compounded topical finasteride for androgenetic alopecia, including formulation details, dosing protocols, efficacy data, and how it compares to oral finasteride and low-dose oral minoxidil.
Read clinical reviewTopical finasteride targets scalp DHT with less systemic absorption than oral finasteride. Learn about clinical evidence, dosing, side effects, and how it compares to oral finasteride for androgenetic alopecia.
Read clinical reviewA physician-reviewed guide to topical minoxidil covering FDA-approved doses, clinical trial results, how it compares to tretinoin, adapalene, tazarotene, and trifarotene, and what to expect from treatment.
Read clinical reviewCompare topical and oral minoxidil for hair loss. Review clinical trial data on efficacy, side-effect profiles, dosing, and practical factors to help you pick the right form.
Read clinical reviewTopical steroid withdrawal (TSW) causes rebound redness, burning, and skin shedding after stopping long-term topical corticosteroids. Learn the symptoms, risk factors, recovery timeline, and steroid-sparing alternatives like dupilumab.
Read clinical reviewA clinician-reviewed guide to topical corticosteroid potency classes, from OTC hydrocortisone (Class VII) to prescription clobetasol (Class I), plus how topical retinoids like tretinoin, adapalene, tazarotene, and trifarotene fit into dermatologic care.
Read clinical reviewA clinical guide to tirbanibulin (Klisyri) for actinic keratosis, including mechanism, efficacy data from KX01-AK-003/004, and comparisons with tretinoin, tazarotene, adapalene, and trifarotene.
Read clinical reviewTralokinumab (Adbry) is an IL-13 inhibitor approved for moderate-to-severe atopic dermatitis in adults. Learn about dosing, trial results, side effects, and how it compares to dupilumab.
Read clinical reviewA physician-reviewed guide to tretinoin (Retin-A), comparing it with adapalene, tazarotene, trifarotene, and topical minoxidil. Covers doses, timelines, side effects, and how to build a retinoid regimen that works.
Read clinical reviewA clinical comparison of tretinoin and retinol for skin health, covering potency, efficacy data, side effects, and how to choose the right retinoid for your goals.
Read clinical reviewTrifarotene (Aklief) is the only FDA-approved topical retinoid selective for the RAR-γ receptor, proven in two Phase 3 trials to clear trunk and facial acne. Learn how it compares to tretinoin, tazarotene, and adapalene, who qualifies, and how to start safely.
Read clinical reviewUpadacitinib (Rinvoq) is a JAK1 inhibitor FDA-approved for moderate-to-severe atopic dermatitis. Learn about clinical trial results, dosing, side effects, and how it compares to dupilumab.
Read clinical reviewEvidence-based guide to choosing your first tretinoin concentration. Covers 0.025% vs 0.05% vs 0.1%, skin-type selection, titration schedules, and retinization timelines backed by dermatology trials.
Read clinical reviewA clinician-reviewed guide to female pattern hair loss, telogen effluvium, and evidence-based treatments including minoxidil, spironolactone, and hormonal therapy.
Read clinical review