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GLP-1 medicine in the news

From a diabetes drug to the Breakthrough of the Year.

GLP-1 medications have been studied in large clinical trials and covered across major media and medical journals. Here is a look at the moment, and where the evidence stands.

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GLP-1 medicine has been reported on by

ScienceThe New York TimesThe Wall Street JournalThe AtlanticTIMEJAMAReuters

Science · 2023

Named the Breakthrough of the Year

Science, one of the world's leading peer-reviewed journals, named GLP-1 medications for obesity its 2023 Breakthrough of the Year, citing evidence that the class blunts obesity-associated health problems beyond weight alone.

Science, Breakthrough of the Year 2023 ↗

The research

Two large trials, published in NEJM

In the STEP 1 trial, adults on weekly semaglutide lost 14.9% of their body weight on average over 68 weeks. In SURMOUNT-1, adults on weekly tirzepatide lost between 16% and 22.5%. Both were published in the New England Journal of Medicine.

See the research breakdown

The cultural moment

One of the most-discussed health topics of the decade

From medical journals to national newspapers, GLP-1 medicine became one of the most widely covered health stories of the decade, shifting the conversation about weight from willpower toward biology and hormones.

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