Just three amino acids
Lys-Pro-Val, the last three amino acids of alpha-MSH, a hormone your body makes.
- As prescribedSupply
- KPV acetateStrength
- Provider reviewedBefore anything ships
The people pictured are models, not patients.
RxLongevity
KPV
Real KPV. A real US pharmacy.
40,000+ products sold · LegitScript certified
Done ordering "research use only" vials? In October 2026, HHS opened KPV, the three-amino-acid tail end of the hormone alpha-MSH, to US 503A pharmacies. Now a licensed provider can prescribe it, and a state-licensed pharmacy makes it for you by name: one ingredient, shipped to your door.
- From a US 503A pharmacy
- Single ingredient
- Provider reviewed
- Free shipping
$199due today
then $199 per month
Continue to checkoutShips in 5 to 7 days
Medication subject to provider approval. Full refund if not approved.
After checkout you complete a short medical review in your member portal, and a US-licensed provider reviews it before your KPV ships.
Full refund if not prescribed Free, discreet shipping
Order today and here is what happens next
- TodayChoose a plan, then a short online intake
- Within about 24 hoursA US-licensed provider reviews your request
- Ships in 5 to 7 daysEstimated ship date, if prescribed
- Full refund
- If a provider does not prescribe it
- Licensed clinicians
- An independent US-licensed clinician reviews every request
- US-licensed pharmacy
- Prepares and ships your prescription
- Discreet delivery
- Plain, unmarked packaging
Common questions
Is this the same KPV sold on research sites?
Same peptide, very different product. Research sites sell vials labeled not for human use, often made overseas, with no one checking whether it fits you. Ours is compounded by a state-licensed US 503A pharmacy from a prescription written for you, with your name and directions on the label.
How is KPV taken?
As your provider directs. Your provider reviews your health history and the directions go on your label.
Is KPV legal to prescribe now?
Yes, under conditions. In October 2026, HHS said it will not take enforcement action against state-licensed 503A pharmacies that compound KPV from a patient-specific prescription and meet the policy's conditions, while FDA finishes its rule. It is still not FDA approved.
LegitScript certifiedCert. 50087439- US-licensed pharmacyPrepares every prescription
- Independent cliniciansUS-licensed, in your state
- 40,000+Products sold
- All 50 statesFree, discreet shipping
- No insurance requiredOne price, shown up front
Breakfast at home
Real KPV. A real US pharmacy.
- 01From a US 503A pharmacy
- 02Single ingredient
- 03Provider reviewed
- 04Free shipping
The people pictured are models, not patients.
Why KPV
Studied in the gut
In mice, KPV in drinking water reduced colitis. In human gut cells it was taken up by the PepT1 transporter.
As your provider directs
Your provider decides the dose and directions, and they go on your label.
Price up front, refund if not prescribed
See every price before you pay. If your provider says no, you get a full refund.
How we compare
KPV, without the waiting room.
HealthRX.comTypical in-person visit
Start online, no appointment or waiting roomBook, travel and wait
A US-licensed clinician reviews your history
Price shown before you startDepends on the visit and insurance
No insurance requiredOften billed through insurance
Delivered to your door in a plain boxPick up at the pharmacy
Full refund if you are not prescribedVisit fees usually apply either way
Understand your treatment
Three amino acids from a hormone you make.
KPV is the tail end of alpha-MSH, a hormone involved in skin color and inflammation signaling. Research has looked at it in the gut and skin. HHS opened it to licensed US 503A pharmacies in October 2026.
A closer look
Three amino acids from a hormone you make.
Lys-Pro-Val
PepT1
One ingredient
Make a more informed choice
KPV vs. alpha-MSH
Alpha-MSH is a 13-amino-acid hormone. KPV is its last three amino acids. Ours is KPV acetate as the only active ingredient, in a vial, used as your provider directs.
A straightforward path to care
Select your plan
Choose your treatment options and complete secure checkout. Then complete the online health intake.
Provider review
A US-licensed provider reviews your intake and prescribes KPV only if it is right for you.
Ships to your door
A state-licensed US 503A pharmacy makes it for you by name and ships it free in plain packaging.
Ongoing support
Message your care team with questions. Your provider can adjust or stop your plan.
- Provider review
- An independent US-licensed clinician reviews every request.
- Free, discreet shipping
- Filled by a US-licensed pharmacy and shipped in discreet packaging.
- Not prescribed?
- You get a full refund for the medication.
About KPV
KPV is the tripeptide Lys-Pro-Val, the last three amino acids of alpha-MSH, a hormone your body makes. Research has looked at it in the gut and skin. In gut cells it is taken up by PepT1, a peptide transporter. Yours is KPV acetate as the only active ingredient, compounded by a US 503A pharmacy and used as your provider directs.
- Three amino acids: Lys-Pro-Val
- KPV acetate, the only active ingredient
- Used as your provider directs
- Prescribed after a US-licensed provider review
Sequence: Lys-Pro-Val (HHS Appendix B, 2026).
Alpha-MSH
a 13-amino-acid hormone your body makes
Lys-Pro-Val
its last three amino acids, KPV
PepT1
the gut transporter that took KPV into cells in a lab study
A three-amino-acid peptide, made for you by a state-licensed US pharmacy.
What the research shows
KPV research is mostly cell and mouse work. Here is what the record shows.
3
amino acids make up KPV: lysine, proline and valine.
HHS Appendix B, 2026
In mice
KPV given in drinking water reduced chemically induced colitis.
Dalmasso et al., Gastroenterology 2008
Oct 2026
HHS opened KPV to licensed US 503A pharmacies, by prescription.
HHS 503A peptide policy, 2026
HealthRX.com or Research-use sites
Two very different ways to get KPV
| HealthRX.com | Research-use sites | |
|---|---|---|
| Who makes it | A state-licensed US 503A pharmacy, from your prescription | Often overseas labs, sold as powder in a vial |
| Labeled for | You, by name, with your provider's directions | "Research use only. Not for human use." |
| Who checks it fits you | A US-licensed provider reviews your health history | No one |
| What is in it | KPV acetate, one ingredient | The seller's own claims |
| Questions later | Message your care team anytime | Seller support, if any |
| Price | Shown up front, full refund if not prescribed | Often less per vial, with no medical review |
What to expect
Here is how your first month goes, from checkout to your first refill.
Today
Choose a plan and do your intake
Checkout takes a few minutes, then a short online health intake.
Day 1 to 2
A provider reviews
A US-licensed provider reviews your intake and may message you with questions.
Within about a week
It arrives
If prescribed, the pharmacy ships it in plain packaging, with your directions on the label.
Each month
Check in and refill
Message your care team anytime. Plans refill on schedule, and you can pause or cancel from your account.
Safety and side effects
KPV is compounded by a US-licensed 503A pharmacy and is not FDA approved. FDA has not reviewed it for safety, effectiveness or quality, and human studies are small. A licensed provider reviews your health history and medicines before deciding whether to prescribe it. It is not for use during pregnancy or breastfeeding, or by anyone under 18. Report side effects to your provider, or to FDA MedWatch at 1-800-FDA-1088.
Common
- Stomach upset
- Skin irritation where a cream is applied
Less common
- Irritation that does not settle after a few days
Seek care
- Signs of an allergic reaction: hives, swelling of the face or throat, or trouble breathing
Human safety data for KPV are limited. Tell your provider about every medicine you take before starting. This is not a complete list of side effects.
Frequently asked questions
What does the research show?
In mice, KPV given in drinking water reduced colitis, and in human gut cells it was taken up by the PepT1 transporter (Dalmasso et al., 2008). Human studies are limited. Your provider will go through what is and is not known.
How much does KPV cost?
Every plan price is on this page before you pay, and longer plans cost less per month. Each plan covers the online provider visit, the medication if prescribed and shipping. If the provider decides it is not right for you, you get a full refund.
Who should not take KPV?
It is not for anyone pregnant, breastfeeding or under 18. Your provider reviews your health history and medicines before deciding.
How fast does it ship?
Usually 3 to 5 days after your provider approves it, in a plain box. Shipping is free.
Can I pause or cancel?
Yes. Plans refill on their own schedule, and you can pause, change or cancel anytime from your account.
Other longevity options
Everyday essentials for your routine.
No prescription needed. Dietary supplements for the daily habits around your care, sold separately from prescription treatment. Ask your provider before adding one to your routine.
Dietary supplements, not medications. These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Approval is never automatic.
An independent US-licensed clinician reviews every request. If they decide the treatment is not right for you, you get a full refund for the medication.
Choose a planNo insurance required
Prescriptions are filled by a US-licensed pharmacy and shipped free, in discreet packaging, on every plan.
LegitScript-certified · Cert 50087439
Compounded medications are prepared by a US-licensed pharmacy and are not reviewed by the FDA for safety or effectiveness. Products are dispensed only after a licensed provider determines they are appropriate. Information here is educational and is not a substitute for medical advice.