Skin
Dapsone appears in a topical acne blend with tretinoin and niacinamide. Its broader research history includes other preparations and conditions.
The catalog lists dapsone 3%, tretinoin 0.07% and niacinamide 4%. An ingredient-level trial of a different topical dapsone concentration would be connected evidence, while a trial of the exact three-ingredient blend would address a closer formulation question.
For acne research, the endpoint also matters: total, inflammatory and non-inflammatory lesion counts are different measures. The publication record needs to retain the measure actually used.
| Product | Listed formulation | Connected ingredient research |
|---|---|---|
| Dapsone Acne Cream | Dapsone 3% / Tretinoin 0.07% / Niacinamide 4% | Dapsone · Tretinoin · Niacinamide |
Publication history
The chart counts records mentioning the search terms in their title or abstract. It includes research beyond skin. Use the period controls to inspect the count.
2026: 120 indexed publications. 2026 includes publications dated through October 5. The earlier bars cover longer periods than the annual bars.
| Period | Publications |
|---|---|
| 1900-1959 | 14 |
| 1960-1969 | 40 |
| 1970-1979 | 290 |
| 1980-1989 | 807 |
| 1990-1999 | 1018 |
| 2000-2009 | 916 |
| 2010-2014 | 515 |
| 2015-2019 | 579 |
| 2020 | 134 |
| 2021 | 135 |
| 2022 | 131 |
| 2023 | 127 |
| 2024 | 120 |
| 2025 | 137 |
| 2026 | 120 |
Source: Europe PMC’s PubMed-indexed records. Retrieved October 5, 2026. The index’s firstPublicationDate field supplies the dates and chart periods; it can normalize a month-only record to the first day of the month. Dates through October 5 are included. Counts can change as the index adds or corrects records.
TITLE_ABS:(dapsone) AND SRC:MED AND FIRST_PDATE:[1900-01-01 TO 2026-10-05]
The focused search returns 90 publications. It narrows the ingredient query to terms connected with its catalog use. Its displayed records remain a search sample, not a ranking of study quality.
TITLE_ABS:(dapsone) AND TITLE_ABS:((topical AND acne)) AND SRC:MED AND FIRST_PDATE:[1900-01-01 TO 2026-10-05]
Dated publications
The timeline combines selected references with a sample from the ingredient search. Dates use the index’s firstPublicationDate field; the PubMed record may distinguish an earlier online date from the print date. Written study notes appear alongside the records that have them. Other entries show the indexed bibliography and link to the paper.
review-article · Review · Journal Article
Alsuwaidan SN, Qadoumi TA. Journal of family medicine and primary care. PMID 41816125.
This record identifies a publication and its indexed publication types. The full paper contains the study methods, population, formulation and results.
Read the PubMed record · Publisher recordWhich dapsone concentration and vehicle were tested? Were tretinoin and niacinamide part of the intervention?
Research data assembled by HealthRX.com from the displayed source records, October 5, 2026. The atlas contains a dated literature search and selected studies; it is not an exhaustive systematic review.