Hormones

Testosterone: the research history.

The catalog includes testosterone cypionate injections and testosterone cream. The ingredient history connects them, while ester, route and concentration separate the formulations.

99,467records matching the ingredient search
2connected formulations
8displayed publication records

How the research connects to the formula

The injection lists testosterone cypionate 200 mg/mL; the cream lists testosterone 50, 100 or 200 mg/mL. These are concentrations in their respective preparations. They are not a cross-route comparison of administered dose or response.

The enclomiphene comparison shown in the hormone guide used testosterone gel. That preparation should remain identified when the study is discussed beside a cream or injection product.

Current HealthRX.com formulation map
ProductListed formulationConnected ingredient research
Testosterone Cypionate InjectionTestosterone Cypionate 200 mg/mLTestosterone
Testosterone CreamTestosterone 50 / 100 / 200 mg/mLTestosterone

Publication history

When the ingredient appeared in the literature

The chart counts records mentioning the search terms in their title or abstract. It includes research beyond hormones. Use the period controls to inspect the count.

2026: 2,612 indexed publications. 2026 includes publications dated through October 5. The earlier bars cover longer periods than the annual bars.

View the chart as a data table
PeriodPublications
1900-19591318
1960-19691449
1970-19796050
1980-198912806
1990-199914078
2000-200918512
2010-201411525
2015-201912818
20202976
20213034
20223035
20232901
20243041
20253312
20262612
Search query and data source

Source: Europe PMC’s PubMed-indexed records. Retrieved October 5, 2026. The index’s firstPublicationDate field supplies the dates and chart periods; it can normalize a month-only record to the first day of the month. Dates through October 5 are included. Counts can change as the index adds or corrects records.

TITLE_ABS:(testosterone) AND SRC:MED AND FIRST_PDATE:[1900-01-01 TO 2026-10-05]

Open this literature search · Download the data

A closer search for this product question

The focused search returns 366 publications. It narrows the ingredient query to terms connected with its catalog use. Its displayed records remain a search sample, not a ranking of study quality.

View the focused query

TITLE_ABS:(testosterone) AND TITLE_ABS:((hypogonadism AND randomized)) AND SRC:MED AND FIRST_PDATE:[1900-01-01 TO 2026-10-05]

Open the focused search

Dated publications

Read individual records in context

The timeline combines selected references with a sample from the ingredient search. Dates use the index’s firstPublicationDate field; the PubMed record may distinguish an earlier online date from the print date. Written study notes appear alongside the records that have them. Other entries show the indexed bibliography and link to the paper.

review-article · Review · Journal Article

Circulating Markers of Cardiovascular Health in Hypogonadism Before and After Testosterone Therapy: Molecular Aspects and Formulation Comparison.

La Vignera S, Condorelli RA. International journal of molecular sciences. PMID 42450305.

This record identifies a publication and its indexed publication types. The full paper contains the study methods, population, formulation and results.

Read the PubMed record · Publisher record

Questions that shape the comparison

Which testosterone preparation and route did the study use? Were the endpoints laboratory values, symptoms or longer-term clinical outcomes?

Source records

Circulating Markers of Cardiovascular Health in Hypogonadism Before and After Testosterone Therapy: Molecular Aspects and Formulation Comparison.La Vignera S, Condorelli RA.International journal of molecular sciences. 2026-07-05. PMID 42450305. review-article, Review, Journal Article.
Re: Testosterone Treatment in Prostate Cancer Survivors with Hypogonadism: A Randomized Clinical Trial.O'Callaghan ME, Selth L, Wittert G.European urology. 2026-07-15. PMID 42457457. Journal Article.
Adiposity, not chronological aging, is the dominant determinant of circulating testosterone in US adult men.Potter AW, Friedl KE.Journal of the Endocrine Society. 2026-08-20. PMID 42661852. research-article, Journal Article.
Effects of Incretin-Based Therapies on Testosterone Levels and Incretin Response in Men with Hypogonadism: A Systematic Literature Review Following PRISMA 2020 Guidelines.La Vignera S, Condorelli R.Pharmaceuticals (Basel, Switzerland). 2026-08-21. PMID 42653816. review-article, Review, Journal Article.
Intermittent enzalutamide in recurrent prostate cancer: testosterone kinetics and related toxicity.Marte JL, Hankin A, Williams M, Gulley JL, Karzai F, Bilusic M, Cordes L, Figg WD, Madan RA, Abel ML.BJU international. 2026-09-13. PMID 42733186. Journal Article.
Long-term endurance running training and testosterone daily variation in ageing men; a comparative cross-sectional study.Bartko B, Oreská Ľ, Buzgó G, Berisha G, Zemaníková V, Okuliarová M, Zeman M, Sedliak M.Experimental physiology. 2026-09-15. PMID 42741997. Comparative Study, research-article, Journal Article.
Weekday-weekend sleep patterning and testosterone outcomes in US men: a cross-sectional analysis of NHANES 2011-2014.Huang R, Huang M, Zhang R.Hormones (Athens, Greece). 2026-09-25. PMID 42791451. Journal Article.
Key Findings on the Efficacy and Safety of Testosterone Therapy from Two Large Randomized Trials.Braga M, Basaria S.The Journal of clinical endocrinology and metabolism. 2026-09-26. PMID 42800050. Journal Article.

Research data assembled by HealthRX.com from the displayed source records, October 5, 2026. The atlas contains a dated literature search and selected studies; it is not an exhaustive systematic review.