Sexual health

Aminophylline: the research history.

Aminophylline is one ingredient in HealthRX.com’s topical arousal cream. Its overall publication history includes subjects beyond sexual health, which makes the condition and route useful filters.

3,789records matching the ingredient search
1connected formulations
8displayed publication records

How the research connects to the formula

The cream also contains ergoloid, pentoxifylline and sildenafil. Research that mentions one ingredient does not necessarily test the four-ingredient product or its topical delivery.

The displayed catalog does not give a numerical concentration for aminophylline in this blend. That field should remain separate from doses used in publications about other routes or conditions.

Current HealthRX.com formulation map
ProductListed formulationConnected ingredient research
Prescription Arousal CreamAminophylline / Ergoloid / Pentoxifylline / SildenafilAminophylline · Ergoloid · Pentoxifylline · Sildenafil

Publication history

When the ingredient appeared in the literature

The chart counts records mentioning the search terms in their title or abstract. It includes research beyond sexual health. Use the period controls to inspect the count.

2026: 15 indexed publications. 2026 includes publications dated through October 5. The earlier bars cover longer periods than the annual bars.

View the chart as a data table
PeriodPublications
1900-1959134
1960-196990
1970-1979484
1980-19891250
1990-1999824
2000-2009423
2010-2014192
2015-2019173
202033
202132
202242
202336
202427
202534
202615
Search query and data source

Source: Europe PMC’s PubMed-indexed records. Retrieved October 5, 2026. The index’s firstPublicationDate field supplies the dates and chart periods; it can normalize a month-only record to the first day of the month. Dates through October 5 are included. Counts can change as the index adds or corrects records.

TITLE_ABS:(aminophylline) AND SRC:MED AND FIRST_PDATE:[1900-01-01 TO 2026-10-05]

Open this literature search · Download the data

A closer search for this product question

The focused search returns 10 publications. It narrows the ingredient query to terms connected with its catalog use. Its displayed records remain a search sample, not a ranking of study quality.

View the focused query

TITLE_ABS:(aminophylline) AND TITLE_ABS:((sexual OR arousal)) AND SRC:MED AND FIRST_PDATE:[1900-01-01 TO 2026-10-05]

Open the focused search

Dated publications

Read individual records in context

The timeline combines selected references with a sample from the ingredient search. Dates use the index’s firstPublicationDate field; the PubMed record may distinguish an earlier online date from the print date. Written study notes appear alongside the records that have them. Other entries show the indexed bibliography and link to the paper.

Comparative Study · Randomized Controlled Trial · Journal Article

Doxapram and aminophylline on bispectral index under sevoflurane anaesthesia: a comparative study.

Wu CC, Lin CS, Wu GJ, Lin YH, Lee YW, Chen JY, Mok MS. European journal of anaesthesiology. PMID 16895622.

This record identifies a publication and its indexed publication types. The full paper contains the study methods, population, formulation and results.

Read the PubMed record · Publisher record

Questions that shape the comparison

Was the research performed on a topical arousal formulation? Did it include the complete ingredient combination?

Source records

Doxapram and aminophylline on bispectral index under sevoflurane anaesthesia: a comparative study.Wu CC, Lin CS, Wu GJ, Lin YH, Lee YW, Chen JY, Mok MS.European journal of anaesthesiology. 2006-08-08. PMID 16895622. Comparative Study, Randomized Controlled Trial, Journal Article.
Comparison of the recovery and respiratory effects of aminophylline and doxapram following total intravenous anesthesia with propofol and remifentanil.Kim DW, Joo JD, In JH, Jeon YS, Jung HS, Jeon KB, Park JS, Choi JW.Journal of clinical anesthesia. 2013-04-11. PMID 23583458. Comparative Study, Research Support, Non-U.S. Gov't, Randomized Controlled Trial, Journal Article.
Amplitude Integrated Electroencephalogram Study of the Effect of Caffeine Citrate on Brain Development in Low Weight Infants with Apnea.Yang D, Zhou B, Jin B, Liu X, Wang Y.Iranian journal of public health. 2019-07-01. PMID 31497549. research-article, Journal Article.
Renal Effects of Aminophylline in Cooled Neonates with Hypoxic-Ischemic Encephalopathy.Baştuğ O, Canpolat A, Kafadar D, Özdemir A, Baştuğ F.American journal of perinatology. 2026-04-03. PMID 41932345. Journal Article.
Potential antidepressant properties of aminophylline in male mice exposed to chronic restraint stress.Samante FI, Galangue CG, Avelino DC, Beltran AJ, Rapada M, Pabia EG, Bustamante NA, Botanas CJ, Samante FL, Bormate KJ, Custodio RJP.Pharmacological reports : PR. 2026-04-07. PMID 41945313. research-article, Journal Article.
Combinational tocolysis: evaluating lower-dose combinations of nifedipine, indomethacin, and aminophylline for tocolytic synergism in pregnant human myometrium.Hossain MR, Paul M, Smith R, Paul JW.American journal of obstetrics and gynecology. 2026-06-04. PMID 42248442. Journal Article.
The effects of locally administered aminophylline in patients undergoing ureteroscopic lithotripsy: a systematic review with exploratory meta-analysis.Alnazari M, Badawi A, Alamri O, Alsehli A, Alamri O, Alhusayni M, Alghamdi A, Mahran A.Frontiers in urology. 2026-06-17. PMID 42389547. Systematic Review, systematic-review, Journal Article.

Research data assembled by HealthRX.com from the displayed source records, October 5, 2026. The atlas contains a dated literature search and selected studies; it is not an exhaustive systematic review.